Daniel J. Buysse, M.D.

UPMC Professor of Sleep Medicine
Professor of Psychiatry and Clinical and Translational Science
University of Pittsburgh School of Medicine
3811 O’Hara St.
Pittsburgh, PA 15213
E: buyssedj@upmc.edu
T: (412) 246-6413
F: (412) 246-5300

Read More


  • BA, University of Michigan (Ann Arbor, MI), 1981
  • MD, University of Michigan (Ann Arbor, MI), 1983
  • Postdoctoral Fellowship, University of Pittsburgh (Pittsburgh, PA), 1987-1989

Current Trainees:

  • Accepting Trainees: Yes

Research Interests:

Dr. Buysse has over 25 years of experience in sleep medicine research. His main areas of focus include sleep assessment and patient-reported outcomes; evaluation and treatment of insomnia; and sleep in aging. He has also investigated sleep in mood disorders, and the interaction between sleep and circadian physiology. This research uses a variety of techniques such as self-report, actigraphy, home and laboratory-based polysomnography, laboratory-based circadian assessments, and functional imaging studies. Dr. Buysse has also conducted clinical trials of behavioral treatment for insomnia.

Dr. Buysse has a long-standing record of teaching and mentoring. He has mentored (or is currently mentoring) 21 post-doctoral fellows, 11 of these as primary research mentor. He has also mentored 12 undergraduate or medical students on research electives. Nine of Dr. Buysse’s previous post-docs have received K awards, eight have obtained NIH R-series funding, and four are still in training. Dr. Buysse is Program Director of an NHLBI-funded T32 program, “Translational Research Training in Sleep Medicine” (HL082610-08), and on the training faculty of two other T32 programs and the institutional KL2 program through the Clinical and Translational Science Institute. Of 8 alumni of the sleep medicine T32, 5 have received K awards. Dr. Buysse is the prior recipient of a K24 award.

Dr. Buysse has served in national and local leadership positions. He is Past President of the American Academy of Sleep Medicine, a former member of the Board of Directors of the Society of Behavioral Sleep Medicine, and Chair of the Sleep Research Network. He has served as Chair of the Biobehavioral Mechanisms of Stress and Health (MESH) study section at NIH, and has served on several NIH panels, including the Program Committee for the NIH State-of-the-Science Conference on the Manifestations and Management of Chronic Insomnia in Adults. Dr. Buysse is Deputy Editor of the journal SLEEP, and has served as Deputy Editor of Journal of Clinical Sleep Medicine, and Associate Editor of Behavioral Sleep Medicine. At the University of Pittsburgh, he served as Director of the Neuroscience Clinical and Translational Research Center, a component of our GCRC then CTSI, for nearly 20 years. He is Co-Chair of the Department of Psychiatry Research Review Committee, and Chair of the K Award Review Program.

Current Research Funding:

  • UH2/UH3 HL125103 (Role: PI): Pragmatic Trial of Behavioral Interventions for Insomnia in Hypertensive Patients, 2014-2019
  • T32 HL082610 (Role: PI): Translational Research Training in Sleep Medicine, 2007-2022.
  • R01 AG047139 (Role: MPI): Sleep Circadian Rhythms, and Cardiometabolic Risk in Retired Shift Workers, 2015-2020.
  • R01 GM113243 (Role: Co-I): Collaborative Research: A Statistical Framework for the Spectral Analysis of Nocturnal Electrophysiological Time Series, 2018-2021.
  • R01 MH105513 (Role: Co-I): A Transdiagnostic Sleep and Circadian Treatment to Improve Community SMI Outcomes, 2014-2018.
  • R01 HL122460 (Role: Co-I): Neighborhood Change: Impact on Sleep and Obesity-Related Health Disparities, 2015-2018.
  • (Matthews) (Role: Co-I): Self-management via Health Kiosk by Community-Residing Older Adults, 2014-2019.
  • R01 AG047139 (Role: Co-I): Sleep, Circadian Rhythms, and Cardiometabolic Risk in Retired Shift Workers, 2015-2020.
  • U01 HL 128954 (Role: Co-I): Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC), 2015-2020.
  • R01 AG056331 (Role: Co-I): Sleep Health Profiles and Mortality Risk in Older Adults: A Multi-Cohort Application of Novel Statistical Methods, 2017-2020.
  • UL1 TGR001857 (Role: Co-I): University of Pittsburgh Clinical and Translational Science Institute: Hub Research Capacity Component (PCI) , 2016-2021.
  • R01 HL131587 (Role: Co-I): Improving Asthma Control Using Internet-based Cognitive-Behavioral Treatment for Insomnia, 2017-2021.
  • R01 AA025626 (Role: Co-I): Proximal Prospective Associations between Circadian Alignment, Reward Function and Alcohol use in Adolescents, 2017-2022.
  • (Patterson) (Role: Co-I): Real-Time Intervention to Reduce Fatigue Among Emergency Service Workers, 2018-2022.
  • R01 MH118312 (Role: Co-I): Longitundinal Study of Sleep Duration, Reward and Cognitive Control Curcuits, and vulnerability for Depressed and Suicidal Ideation During Adolescence, 2018-2023.

Selected Publications:

  1. Levenson JC, Kay DB, Buysse DJ. The pathophysiology of insomnia. Chest 147(4): 1179-1192, 2015.  PMCID: PMC4388122
  2. Kay DB, Buysse DJ, Germain A, Hall MH, Monk TH. Subjective-objective sleep discrepancy among older adults: Associations with insomnia diagnosis and insomnia treatment. Journal of Sleep Research 24(1):32-39, 2015. PMCID: PMC474029
  3. Buysse DJ. Sleep health: Can we define it? Does it matter? Sleep, 37(1):9-17, 2014. PMCID: PMC3902880
  4. Buysse DJ. Insomnia. JAMA-Journal of the American Medical Association, 309(7):706-716, 2013. PMCID: PMC3632369
  5. Yu L, Buysse DJ, Germain A, Moul DE, Stover A, Dodds NE, Johnston KL, Pilkonis PA. Development of short forms from PROMISTM Sleep Disturbance and Sleep-Related Impairment Item Banks. Behavioral Medicine, 10(1): 6-24, 2012. PMCID: PMC3261577
  6. Buysse DJ, Germain A, Hall M, Monk TH, Nofzinger EA. A neurobiological model of insomnia. Drug Discovery Today: Disease Models, 8(4): 129-137, 2011. PMCID: PMC3212043.
  7. Buysse DJ, Germain A, Moul DE, Franzen PL, Brar LK, Fletcher ME, Begley A, Houck PR, Mazumdar S, Reynolds CF, Monk TH. Efficacy of brief behavioral treatment for chronic insomnia in older adults. Archives of Internal Medicine, 171(10):887-895, 2011. PMCID: PMC3101289
  8. Buysse DJ, Yu L, Moul DE, Germain A, Stover A, Dodds NE, Johnston KL, Shablesky-Cade MA, Pilkonis PA. Development and validation of patient-reported outcome measures for sleep disturbance and sleep-related impairments. Sleep, 33(6):781-92, 2010. PMCID: PMC2880437
  9. Buysse DJ, Angst J, Gamma A, Ajdacic V, Eich D, Rossler W. Prevalence, course and comorbidity of insomnia and depression in young adults. Sleep, 31(4):473-80, 2008. PMCID: PMC2279748
  10. Nofzinger EA, Nissen C, Germain A, Moul D, Hall M, Price JC, Miewald JM, Buysse DJ. Regional cerebral metabolic correlates of WASO during sleep in insomnia. Journal of Clinical Sleep Medicine, 2(3):316-22, 2006.
  11. Nofzinger EA, Buysse DJ, Germain A, Price JC, Miewald JM, Kupfer DJ. Functional neuroimaging evidence of hyperarousal in insomnia. American Journal of Psychiatry, 161(11):2126-31, 2004.
  12. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2):193-213, 1989.

Complete list of published work: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40800059/?sort=date&direction=ascending


PubMed Author Search

Adam D Bramoweth, PhD, DBSM

Research Health Scientist & Staff Psychologist
VA Pittsburgh Healthcare System

Research Office Building (151RU)
University Drive C
Pittsburgh, PA 15240

E:  Adam.Bramoweth@va.gov

T: 412-360-2806

Mazen El Ali, MD

Clinical Assistant Professor of Medicine
Associate Program Director, Sleep Medicine Fellowship
Director, Sleep Laboratory, UPMC Mercy

3459 Fifth Avenue
NW 628.8 Montefiore Hospital
Pittsburgh, PA 15213

E: elalim2@upmc.edu

T: 412-864-2089 

F: 412-692-2888 

Assistant: Cynthia Hatfield
Assistant Phone: 412-647-2461
Assistant Email: hatfieldca2@upmc.edu


Peter L. Franzen, Ph.D.

Associate Professor 
3811 O’Hara Street, Room E-1118
Pittsburgh, PA 15213

E: franzenpl@upmc.edu

T: 412-586-9038
F: 412-246-5300

Read More

Anne Germain, Ph.D.

Associate Professor of Psychiatry & Psychology
Director, Sleep and Chronobiology Laboratories
University of Pittsburgh School of Medicine
Military Sleep Tactics and Resilience Research Program
3811 O’Hara Street
Sterling Plaza 240
Pittsburgh, PA 15213

E: ang2@pitt.edu
T: 412-383-2150
Website: https://www.veteranssleep.pitt.edu

Read More


  • B. Sc., McGill University (Montréal, Québec, Canada), 1996
  • M. Ps., Université de Montréal, (Montréal, Québec, Canada), 2000
  • Ph.D., Université de Montréal, (Montréal, Québec, Canada), 2001
  • Postdoctoral Fellowship, University of Pittsburgh (Pittsburgh, PA), 2001-2005

Research Interests:

Dr. Germain’s research program focuses on the pathophysiological, neural underpinnings, and treatments of sleep disturbances comorbid with stress-related disorders, with a special emphasis on posttraumatic stress disorder (PTSD) in military populations. Her federally-funded research project focuses on the relationship between sleep and neural circuits involved in anxiety, mood, and substance use disorders. Within the context of close multidisciplinary collaborations, her research program also includes studies aimed at examining sleep in traumatic injury, including traumatic brain injury, and the moderating roles of genetic and environmental factors on neural responses to threats and rewards. Dr. Germain is a committed research mentor for medical students, undergraduate and graduate students, as well as post-doctoral fellows and residents, and junior faculty members. In addition, she is the Director of the Course in Scientific Management Leadership at the University of Pittsburgh and serves as faculty on several T32 postdoctoral training grants.

Current Research Funding:

  • W81XWH-12-2-0024 1129300 (Role: PI). US Department of Defense– USAMRAA. Dose-dependent effects of sleep disruption on fear responses and reward processing. 2012-2017.
  • W81XWH-13-PHTBI- PT130572 (Roe: Co-PI). US Department of Defense– USAMRAA. Uncovering Physiological Markers
    Linking Sleep and PTSD. 2015-2018.
  • W81XMH-10-2-0178 (Role: Co-I). Military Suicide Research Consortium, Defense Health Program. A Behavioral Sleep
    Intervention for Suicidal Behaviors in Military Veterans: A Randomized Controlled Pilot. MSRC.
  • HD069375 (Role Co-I; site PI). Security and Vigilance in Military Couples: A Dynamic Model of Sleep, Interpersonal
    Relationships, and Health. 2011-2015.
  • BAA 13-1 13154004. US Department of Defense– USAMRAA. (Role: Co-I) Targeted Evaluation, Action & Monitoring of
    Traumatic Brain Injury (TEAM-TBI). 2013-2015.

Selected Publications (Selected from 96 publications; * denotes work conducted by trainee):

  1. Germain A, Nielsen TA. Impact of imagery rehearsal treatment on distressing dreams, psychological distress, and sleep parameters in nightmare patients. Behavioral Sleep Medicine, 1:140-154, 2003.
  2. Germain A, Nielsen TA. Sleep pathophysiology in PTSD and idiopathic nightmare sufferers. Biological Psychiatry, 54:1092-1098, 2003.
  3. Germain A, Hall M, Krakow B, Shear MK, Buysse DJ. A brief sleep scale for posttraumatic stress disorder: Pittsburgh Sleep Quality Index Addendum for PTSD. Journal of Anxiety Disorders, 19:233-244, 004.
  4. Germain A, Buysse DJ, Shear MK, Fayyad R, Austin C. Clinical correlates of sleep disturbance severity in posttraumatic stress disorder. Journal of Traumatic Stress, 17:477-484, 2004.
  5. Germain A, Buysse DJ, Wood AM, Nofzinger EA. Functional neuroanatomical correlates of eye movements during rapid eye movement (REM) sleep in depressed patients. Psychiatry Research: Neuroimaging, 30(3):259-68, 2004.
  6. Germain A, Nofzinger EA, Kupfer DJ, Buysse DJ. Neurobiology of NREM sleep in depression: Further evidence for hypofrontality and thalamic dysregulation. American Journal of Psychiatry, 161:1856-1863, 2004.
  7. Germain A, Caroff K, Buysse DJ, Shear MK. Sleep quality in complicated grief. Journal of Traumatic Stress, 18(4):343-346, 2005.
  8. Germain A, Shear MK, Monk TH, Houck PR, Reynolds CF III, Frank E, Buysse DJ. Treating complicated grief: Effects on sleep quality. Behavioral Sleep Medicine, 4(3):152-163, 2006.
  9. Nofzinger EA, Nissen C, Germain A, Moul DE, Hall M, Price JC, Miewald JM, Buysse DJ. Regional cerebral metabolic correlates of WASO during NREM sleep in insomnia. Journal of Clinical Sleep Medicine, 2(3):316-322, 2006.
  10. Germain A, Moul DE, Franzen PL, Miewald JM, Reynolds CF III, Monk TH, Buysse DJ. Effects of a brief behavioral treatment for late-life insomnia: Preliminary findings. Journal of Clinical Sleep Medicine, 2(4): 403-406, 2006.
  11. Germain A, Nofzinger EA, Meltzer CC, Wood AM, Kupfer DJ, Moore RY, Buysse DJ. Diurnal variation in regional brain glucose metabolism in depression. Biological Psychiatry, 62:438-445, 2007. PMCID: PMC3195370
  12. Germain A, Shear MK, Hall M, Buysse DJ. Effects of a brief behavioral treatment for PTSD-related sleep disturbances: A pilot study. Behaviour and Research Therapy, 45(3): 627-632, 2007.
  13. Germain A, Buysse DJ, Nofzinger EA. Sleep-specific mechanisms underlying posttraumatic stress disorder: Integrative review and neurobiological hypotheses. Sleep Medicine Reviews, 12(3):185-195, 2008. PMCID: PMC2490669
  14. Germain A, Kupfer DJ. Circadian Rhythm Disturbances in Depression. Human Psychopharmacology: Clinical and Experimental, 23:571-585, 2008. PMCID: PMC2612129
  15. Troxel W, Germain A. Insecure attachment is an independent correlate of objective sleep disturbances in military veterans. Sleep Medicine, 12:860-865, 2011. PMCID: PMC21925945
  16. Alarcon LH, Germain A, Clontz AS, Roach E, Nicholas DH, Zenati M, Peitzman AB, Sperry JL. Predictors of post-traumatic stress disorder following civilian trauma: highest incidence and severity of symptoms after assault. Journal of Trauma and Acute Care Surgery, 72(3):629-637, 2012.
  17. Germain A, Richardson R, Moul DE, Mammen O, Haas G, Forman SD, Rode N, Begley A., Nofzinger EA. Placebo-controlled comparison of prazosin and cognitive-behavioral treatments for sleep disturbances in US Military Veterans. Journal of Psychosomatic Research, 72(2):89-96, 2012. PMCID: PMC3267960
  18. *Insana S, Kolko DJ, Germain A. Early-life trauma is associated with rapid eye movement sleep fragmentation among military veterans. Biological Psychology, 89(3):570-579, 2012. PMCID: PMC3299844
  19. *Hasler BP, Germain A, Nofzinger E, Kupfer DJ, Krafty RT, Rothernberger SD, James JA, Bi W, Buysse DJ. Chronotype and diurnal patterns of positive affect and affective neural circuitry in primary insomnia. Journal of Sleep Research, 21(5): 515-526, 2012. PMCID: PMC3371278
  20. *Cohen DJ, Begley A, Alman JJ, Cashmere DJ, Pietrone RN, Seres RJ, Germain A. Quantitative EEG during REM and NREM sleep in combat-exposed veterans with and without Posttraumatic Stress Disorder. Journal of Sleep Research, 22(1):76-82, 2013. PMCID: PMC3488164
  21. Troxel WM, Germain A, Buysse DJ. Clinical management of insomnia with Brief Behavioral Treatment (BBTI). Behavioral Sleep Medicine, 10(4):266-279, 2012. PMCID: PMC3622949
  22. Germain A, James J, Insana S, Herringa RJ, Mammen O, Price J, Nofzinger EA. A window into the invisible wound of war: Functional neuroimaging of REM sleep in returning combat veterans with PTSD. Psychiatry Research, 211(2):176-9, 2013. PMCID: PMC3570584
  23. *Insana SP, Hall M, Buysse DJ, Germain A. Validation of the pittsburgh sleep quality index addendum for posttraumatic stress disorder (PSQI-A) in U.S. male military veterans. Journal of Traumatic Stress, 26(2):192-200, 2013. PMCID: PMC3746481
  24. Germain A. Sleep disturbances as the hallmark of PTSD: Where are we now? American Journal of Psychiatry, 170(4):372-382, 2013. PMCID: PMC4197954
  25. *Herringa RJ, Phillips M, Almeida J, Insana S, Germain A. Post-traumatic stress symptoms correlate with smaller subgenual cingulate, caudate, and insula volumes in non-medicated combat veterans. Psychiatry Research, 203(2-3):139-45, 2012. PMCID: PMC3466380
  26. *Herringa RJ, Phillips ML, Fournier JC, Kronhaus DM, Germain A. Childhood and adult trauma both correlate with dorsal anerior cingulate activation to threat in combat veterans. Psychological Medicine, 43(7):1533-42, 2013. PMCID: PMC3686816
  27. *McDowell AL, Filippone AB, Balbir A, Germain A, O’Donnell CP. Mild transient hypercapnia as a novel fear conditioning stimulus allowing re-exposure during Sleep. PLoS One, 8(6):e67435, 2013. PMCID: PMC3693948
  28. Troxel M, Conrad T, Germain A, Buysse J. Predictors of treatment response to brief behavioral treatment of insomnia (BBTI) in older adults. Journal of Clinical Sleep Medicine, 15; 9(12):1281-9, 2013. PMCID: PMC3836339
  29. *Bramoweth A, Germain A. Deployment-related insomnia in military personnel and veterans. Current Psychiatry Reports, 15(10):401, 2013. PMCID: PMC3832138
  30. *Ebdlahad S, Nofzinger EA, James JA, Buysse DJ, Price JC, Germain A. Comparing neural correlates of REM sleep in posttraumatic stress disorder and depression: A neuroimaging study. Psychiatry Research Neuroimaging, 30; 214(3):422-8, 2013. PMCID: PMC3869237
  31. *Casement MD, Germain A. Is group imagery rehearsal for posttrauma nightmares as good at reducing PTSD symptoms as group treatment for PTSD? Psychological Trauma: Theory, Research, Practice, and Policy, 6(3), 259-260, 2014.
  32. *Stocker R, Cieply M, Paul B, Henry L, Kontos A, Germain A. Combat-related blast exposure and traumatic brain injury influence brain glucose metabolism during REM sleep in military veterans. Neuroimage, 2;99C:207-214, 2014. PMCID: PMC4112017
  33. Mysliwiec V, O’Reilly B, Polchinski J, Kwon HP, Germain A, Roth BJ. Trauma associated sleep disorder: A proposed parasomnia encompassing disruptive nocturnal behaviors, nightmares and REM sleep without atonia in trauma survivors. Journal of Clinical Sleep Medicine, 10(10), 1143-1148, 2014. PMCID: PMC4173093
  34. Germain A, Richardson R, Stocker R, Mammen O, Hall M, Bramoweth A, Begley A, Rode N, Frank E, Hass G, Buysse DJ. Treatment for insomnia in combat-exposed OEF/OIF military veterans: preliminary randomized controlled trial. Behaviour Research and Therapy, 61:78-88, 2014. PMCID: PMC4180045
  35. Lotrich F, Germain A. Decreased delta sleep ratio and elevated alpha power predict vulnerability to depression during interferon-alpha treatment. Acta Neuropsychiatrica, in press. PMCID: In process
  36. Ellis JG, Cushing T, Germain A. Treating acute insomnia: A randomized control trial of a ‘single-shot’ of cognitive behavior therapy for insomnia. Sleep, in press. PMCID: In process
  37. Edinger JD, Buysse DJ, Deriy L, Germain A, Lewin DS, Ong JC, Morgenthaler TI. Quality measures for the care of patients with insomnia. Journal of Clinical Sleep Medicine (in press). PMCID: In process
  38. Mysliwiec V, Williams S, Baxter T, Germain A, O’Reilly B, Luxton DD. Preventing sleep casualties: Understanding the unique aspects of sleep and sleep disorders in active duty service members. Combat Stress, 3(4):8-25, 2014.
  39. Germain A. Resilience and readiness through restorative sleep. Sleep, 38(2): 171-173, 2015.

Brant P. Hasler, Ph.D.

Associate Professor of Psychiatry, Psychology, and Clinical and Translational Science
Department of Psychiatry
3811 O’Hara Street, Room E-1127
Pittsburgh, PA 15213

E: haslerbp@upmc.edu
T: 412-246-6413
F: 412-246-5300

Read More

Current trainees:

  • Garrett Hisler, PhD (primary mentor)
  • Chelsea Vadnie, PhD (secondary mentor)
  • Accepting trainees: Yes


  • BA, Neuroscience & Behavior, Wesleyan University (Middletown, CT), 1994
  • MS, Clinical Psychology, University of Arizona (Tucson, AZ), 2005
  • PhD, Clinical Psychology, University of Arizona (Tucson, AZ), 2009
  • Postdoctoral Fellowship, Translational Research Training in Sleep Medicine (T32), University of Pittsburgh (Pittsburgh, PA), 2009-2012

Research Interests:

Dr. Hasler’s research focuses on the role of sleep and circadian rhythms in regulating affect and motivation, particularly as relevant to affective disorders and substance abuse. In addition to his research program, Dr. Hasler is actively engaged in research mentorship and clinical supervision, as well as direct clinical practice, and is the Co-Director of our accredited Behavioral Sleep Medicine training fellowship.

Current Research Funding:

  • R01 AA025626 (Hasler): Proximal prospective associations between circadian alignment, reward function and alcohol use in adolescents, 2018-2012. Role: PI. NIH RePORTER link
  • R01 DA044143 (Hasler): Delayed sleep phase and risk for adolescent substance use, 2019-2023. Role: PI. NIH RePORTER link
  • R01 AA026249 (Hasler/Pedersen): Positive and negative reinforcement pathways underlying sleep and alcohol use associations, 2019-2023. Role: MPI. NIH RePORTER link
  • AA021690 (Clark): National Consortium on Alcohol and NeuroDevelopment in Adolescence, 2012-2017. Role: Co-I NIH RePORTER link


Selected Publications:

  1. Hasler BP, Bruce S, Scharf D, Clark DB. Circadian misalignment and weekend alcohol use in late adolescent drinkers: Preliminary evidence. Chronobiology International. (in press)
  2. Lebensohn-Chialvo F, Rohrbaugh MJ, Hasler BP, Shoham V. Fidelity failures in family therapy for adolescent drug abuse: A clinical analysis. Family Process. (in press)
  3. *Taylor BJ, Hasler BP. Chronotype and mental health: Recent advances. Current Psychiatry Reports, 20(8), 59-69, 2018.
  4. Logan RW, Hasler BP, Forbes EE, Franzen PL, Torregrossa MM, Huang YH, Buysse DJ, Clark DB, McClung CA.  Impact of sleep and circadian rhythms on addiction vulnerability in adolescents.  Biological Psychiatry, 83, 987-996, 2018.
  5. Hasler BP, Franzen PL, de Zambotti M, Prouty D, Brown SA, Tapert SF, Pfefferbaum A, Pohl KM, Sullivan EV, DeBellis MD, Nagel BJ, Colrain IM, Baker FC, Clark DB. Eveningness and later sleep timing are associated with greater risk for alcohol and marijuana involvement: Initial findings from the NCANDA study. Alcoholism: Clinical and Experimental Research, 41, 1154-1165, 2017. PMCID: PMC5488322
  6. Hasler BP, Casement MD, Sitnick SL, Shaw DS, Forbes EE. Eveningness among late adolescent males predicts neural reactivity to reward and alcohol dependence two years later. Behavioural Brain Research, 327, 112-120, 2017. PMCID: PMC5483989
  7. *Mike T, Sitnick SL, Shaw DS, Forbes EE, Hasler BP. The hazards of bad sleep: Sleep duration and quality as predictors of adolescent alcohol and cannabis use. Drug and Alcohol Dependence, 168, 335-339, 2016. PMCID: PMC5086262
  8. Wong PM, Hasler BP, Kamarck TW, Muldoon MF, Manuck SB. Social jetlag, chronotype, and cardiometabolic risk. The Journal of Clinical Endocrinology & Metabolism, 100, 4612-4620, 2015. PMCID: PMC4667156
  9. Miller MA, Rothenberger SD, Hasler BP, Donofry SD, Wong PM, Manuck SB, Kamarck KA, Roecklein KA. Chronotype predicts positive affect rhythms measured by ecological momentary assessment. Chronobiology International, 32, 376-384, 2015. PMCID: PMC4458846
  10. Gunn HE, Buysse DJ, Hasler BP, Begley A, Troxel WM. Sleep concordance in couples is associated with relationship characteristics. Sleep, 38, 933-939, 2015. PMCID: PMC4434560
  11. Hasler BP, Forbes EE, Franzen PL. Time-of-day differences and short-term stability of the neural response to monetary reward: A pilot study. Psychiatry Research: Neuroimaging, 224, 22-27. PMCID: PMC4157087
  12. Hasler BP, Soehner AM, Clark DB. Sleep and circadian contributions to adolescent alcohol use disorder. Alcohol. (in press) (PMCID: in process
  13. Hasler BP, Martin CS, Wood DS, Rosario B, Clark DB. A longitudinal study of insomnia and other sleep complaints in adolescents with and without alcohol use disorders. Alcoholism: Clinical and Experimental Research, 38, 2225-2233, 2014. PMCID: PMC4146702
  14. Frank E, Sidor MM, Gamble KL, Cirelli C, Sharkey KM, Hoyle N, Tikotzky L, Talbot LS, McCarthy MJ, Hasler BP. Circadian clocks, brain function, and development. Annals of the NY Academy of Sciences. 1306, 43-67, 2013. PMID: 24329517
  15. Hasler BP, Sitnick SL, Shaw DS, Forbes EE. An altered neural response to reward may contribute to alcohol problems among late adolescents with an evening chronotype. Psychiatry Research: Neuroimaging, 214, 357-364, 2013. PMCID: PMC3852171
  16. Hasler BP, Clark DB.   Circadian misalignment, reward functioning, and adolescent alcohol involvement.   Alcoholism: Clinical and Experimental Research. 37(4), 558-565, 2013. PMCID: PMC3843484
  17. Hasler BP, Dahl RE, Holm SM, Jakubcak JL, Ryan ND, Silk JS, Phillips ML, Forbes EE.  Weekend-weekday advances in sleep timing are associated with altered reward-related brain function in healthy adolescents. Biological Psychology, 91, 334-341, 2012.  PMCID: PMC3490026
  18. Velo J, Stewart JL, Hasler BP, Towers DN, Allen JJB. Should it matter when we record? Time of year and time of day as factors influencing frontal EEG asymmetry.  Biological Psychology, 91, 283-291, 2012. PMCID: PMC3530616
  19. Roecklein KA, Wong PM, Franzen PL, Hasler BP, Wood-Vasey WM, Nimgaonkar VL, Miller MA, Ferrell RE, Manuck SB. Melanopsin gene variations interact with season to predict sleep timing and chronotype. Chronobiology International, 29, 1036-1047, 2012. PMCID: PMC3724237
  20. Hasler BP, Germain A, Nofzinger EA, Kupfer DJ, Krafty RT, Rothenberger SD, James JA, Bi W, Buysse DJ.  Chronotype and diurnal patterns of positive affect and affective neural circuitry in primary insomnia.  Journal of Sleep Research, 21, 515-526, 2012. PMCID: PMC3371278
  21. Hasler BP, Smith LJ, Cousins JC, Bootzin RR.  Circadian rhythms, sleep, and substance abuse.  Sleep Medicine Reviews, 16(1), 67-81, 2012. PMCID: PMC3177010
  22. Hasler BP, Troxel WM.  Couples’ nighttime sleep efficiency and concordance: Evidence for bidirectional associations with daytime relationship functioning.  Psychosomatic Medicine, 72(8), 794-801, 2010. PMCID: PMC2950886.
  23. Hasler BP, Buysse DJ, Kupfer DJ, Germain A.  Phase relationships between core body temperature, melatonin, and sleep are associated with depression severity:  Further evidence for circadian misalignment in non-seasonal depression.  Psychiatry Research, 178(1), 205-207, 2010. PMCID: PMC2914120.
  24. Britton WB, Bootzin, RR, Cousins JC, Hasler BP, Peck T, Shapiro SL. The contribution of mindfulness practice to a multi-component behavioral sleep intervention following substance abuse treatment in adolescents: A treatment development study. Substance Abuse, 31(2), 86-97, 2010. †
  25. Hasler BP, Allen JJB, Sbarra DA, Bootzin RR, Bernert RA. Morningness-eveningness and depression: Preliminary evidence for the role of BAS and positive affect.  Psychiatry Research, 176, 166-173, 2010. PMCID: PMC2844473.
  26. Rohrbaugh MJ, Shoham V, Butler EA, Hasler BP, Berman JS. Affective synchrony in dual- and single-smoker couples: Further evidence of “symptom-system fit”?  Family Process, 48(1), 55-67, 2009. PMCID: PMC2774814.
  27. Hasler BP, Mehl MR, Bootzin RR, Vazire S. Preliminary evidence of diurnal rhythms in everyday behaviors associated with positive affect.  Journal of Research in Personality, 42(6), 1537-1546, 2008. 
  28. Hasler BP, Bootzin RR, Cousins JC, Fridel K, Wenk GL. Circadian phase in sleep-disturbed adolescents with a history of substance abuse. Behavioral Sleep Medicine, 6(1), 55-73, 2008.
  29. Lewy AJ, Emens JS, Sack RL, Hasler B, Bernert RA.  Zeitgeber hierarchy in humans: resetting the circadian phase positions of blind people using melatonin. Chronobiology International, 20(5), 837-852, 2003. 
  30. Lewy AJ, Emens JS, Sack RL, Hasler BP, Bernert RA.  Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period.  Chronobiology International, 19(3), 649-658, 2002. 
  31. Lewy AJ, Hasler BP, Emens JS, Sack RL.  Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin.  Neuroscience Letters, 313(3), 158-160, 2001.
  32. Lewy AJ, Bauer VK, Hasler BP, Kendall AR, Pires MLN, Sack RL.  Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.  Brain Research, 918(1-2), 96-100, 2001.

Complete List of Published Work in MyBibliography:  https://www.ncbi.nlm.nih.gov/sites/myncbi/brant.hasler.1/bibliography/43827584/public/?sort=date&direction=descending

Martica H. Hall, Ph.D.

Professor Department of Psychiatry
3811 O’Hara Street
Room E-1131
Pittsburgh, PA 15213

T: 412-246-6431
F: 412-246-5300

Read More

Current Trainees:

  • Katherine Duggan, PhD, Jonna Morris, PhD
  • Graduate Student: Marissa Bowman
  • Accepting Trainees: Yes


  • MS, Medical Psychology, Uniformed Services University of the Health Sciences (Bethesda, MD), 1993
  • PhD, Biopsychology, University of Pittsburgh (Pittsburgh, PA), 1995

Research Interests:

Dr. Hall’s research program bridges the traditionally independent fields of behavioral medicine and sleep medicine.  Her research focuses on the pathways through which psychological and social factors affect sleep and their downstream consequences to health and functioning, with an emphasis on diseases of aging.  She has evaluated these relationships in diverse populations across the lifespan, focusing mainly on mid- to adults at increased risk for cardiometabolic disease including caregivers, women during the menopausal transition, individuals with sleep and psychiatric disorders, and adults affected by racial/social disparities.  She has given national and international workshops on the assessment of sleep, including self-report indices of sleep duration in studies of sleep health.  Dr. Hall has also developed and refined innovative protocols for the assessment of ecologically valid and reliable measures of sleep health including ambulatory polysomnography, wrist actigraphy, and heart rate variability during sleep.

Committed to the future of sleep and circadian science, Dr. Hall is a dedicated mentor. She works with trainees across the educational continuum from undergraduates, to graduate and medical students, postdoctoral fellows, and junior faculty. Dr. Hall directs the training seminar for the “Translational Research Training in Sleep Medicine” training program (T32 HL082610), and serves as training faculty on four other NIH-funded T32 programs. In recognition of her dedication to training, Dr. Hall is the recipient of the Sleep Research Society’s 2019 Mary Carskadon Outstanding Educator Award.

Research Funding:

  • R01 AG047139 (Role: MPI). Sleep, Circadian Rhythms, and Cardiometabolic Risk in Retired Shift Workers, 2015-2020
  • R01 HL126770 (Role: Site PI). Sleep, Stress, and Arterial Stiffness. 2016-2020
  • R01 HL136205 (Role: Site PI). Sleep Disturbance as a Mechanism for Ischemic Heart Disease in PTSD. 2017-2021
  • R01 AG056331 (Role: Co-I)   Sleep Health Profiles and Mortality Risk in Older Adults: A Multi-Cohort Application of Novel Statistical  Methods. 2017-2020
  • R01 HL142064 (Role: Site PI). Sleep and Circadian Mechanisms Contributing to Disparity in Prevalence of Hypertension Between Black and White Americans. 2018-2022
  • R01 GM113243 (Role: Co-I). A Statistical Framework for the Spectral Analysis of High Dimensional Physiological Time Series Signal, 2018-2021. NIH RePORTER Link
  • U01 AG012546 (Role: Co-I). Study of Women’s Health Across the Nation, 2014-2019. NIH RePORTER Link

Refereed Publications (* denotes work conducted by mentored trainees):

  1. Zakowski SG, Hall M. , Baum A. Stress, stress management, and the immune system. Applied and preventive psychology: Current Scientific Perspectives, 1:1-13, 1992.
  2. Baum A, Cohen L, Hall M. Control and intrusive memories as possible determinants of chronic stress. Psychosomatic Medicine,55:274-86, 1993.
  3. Patterson SM, Zakowski SG, Hall M, Cohen L, Wollman K, Baum A. Psychological stress and platelet activation: Differences in platelet reactivity in healthy men during active and passive stressors. Health Psychology, 13:34-8, 1994.
  4. Zakowski SG, Cohen L, Hall M, Wollman K, Baum A. Differential effects of active and passive laboratory stressors on immune function in a group of healthy men. International Journal of Behavioral Medicine, 1:163-84, 1994.
  5. Hall M, Baum A. Intrusive thoughts as determinants of distress in parents of children with cancer. Journal of Applied Social Psychology, 25:1215-30, 1995.
  6. McCann UD, Thorne D, Hall M, Avery W, Sing H, Thomas M, Belenky G. The effects of L-dihydroxyphenylalanine on alertness and mood in alpha-methyl-para-tyrosine-treated normal volunteers: Further evidence for the role of catecholamines in arousal and anxiety. Neuropsychopharmacology, 13:41-52, 1995.
  7. Reynolds CF, Frank E, Perel JM, Mazumdar S, Dew MA, Begley A, Houck PR, Hall M, Mulsant B, Shear MK, Miller MD, Cornes C, Kupfer DJ. High relapse rates after discontinuation of adjunctive mediation in elderly patients with recurrent major depression. American Journal of Psychiatry, 153:1418-22, 1996.
  8. Dew MA, Reynolds CF, Houck P, Hall M, Buysse DJ, Frank E, Kupfer DJ. Temporal profiles of the course of depression during treatment: Predictors of pathways toward recovery in the elderly. Archives of General Psychiatry, 54:1016-24, 1997.
  9. Hall M, Buysse DJ, Dew MA, Prigerson HG, Kupfer DJ, Reynolds CF. Intrusive thoughts and avoidance behaviors are associated with sleep disturbances in bereavement-related depression. Depression and Anxiety, 6:106-12, 1997.
  10. McDermott OD, Prigerson HG, Reynolds CF, Houck PR, Dew MA, Hall M, Mazumdar S, Buysse DJ, Hoch CC, Kupfer DJ. Sleep in the wake of complicated grief: A preliminary report. Biological Psychiatry, 41:710-6, 1997.
  11. Pasternak RE, Prigerson H, Hall M, Miller MD, Fasiczka A, Mazumdar S, Reynolds CF. The post-treatment illness course of depression in bereaved elders: High relapse/recurrence rates. American Journal of Geriatric Psychiatry, 5:54-8, 1997.
  12. Reynolds CF, Buysse DJ, Dew MA, Hoch CC, Hall M, Brunner DP, Begley A, Houck PR, Mazumdar S, Perel JM, Kupfer DJ. Maintenance nortriptyline effects on homeostatic control of sleep in elders with recurrent major depression: Double-blind, placebo- and plasma-level controlled evaluation. Biological Psychiatry, 42:560-7, 1997.
  13. Buysse DJ, Hall M, Tu XM, Land S, Houck PR, Cherry CR, Kupfer DJ, Frank E. Latent structure of EEG sleep variables in depressed and control subjects: Descriptions and clinical correlates. Psychiatry Research, 79:105-22, 1998.
  14. Hall M, Baum A, Buysse DJ, Prigerson HG, Kupfer DJ, Reynolds CF. Sleep as a mediator of the stress-immune relationship. Psychosomatic Medicine, 60:48-51, 1998.
  15. Hall M, Bromberger JT, Matthews KA: Socioeconomic status as a correlate of sleep in African-American and Caucasian women. Socioeconomic Status and Health in Industrial Nations: Social, Psychological, and Biological Pathways. Adler NE, Marmot M, McEwen BS, Stewart J (Eds.), Annals of the New York Academy of Sciences, 427-430, 1999.
  16. Hall M, Buysse DJ, Nowell PD, Nofzinger EA, Houck P, Reynolds CF, Kupfer DJ. Symptoms of stress and depression as correlates of sleep in primary insomnia. Psychosomatic Medicine, 62:227-30, 2000.
  17. Buysse DJ, Hall M, Begley A, Cherry CR, Houck PR, Land S, Ombao H, Kupfer DJ, Frank E. Sleep and treatment response in depression: New findings using power spectral analysis. Psychiatry Research, 103:51-67, 2001.
  18. Zakowski SG, Hall M, Klein LC, Baum A. Appraised control, coping and stress in a community sample: A test of the goodness-of-fit hypothesis. Annals of Behavioral Medicine, 23:158-65, 2001.
  19. Hoch CC, Reynolds CF, Buysse DJ, Monk TH, Nowell PD, Begley A, Hall M, Dew MA. Protecting sleep quality in later life: A pilot study of bed restriction and sleep hygiene. Journal of Gerontology Psychological Sciences, 56:52-9, 2001.
  20. Reynolds CF, Buysse DJ, Nofzinger EA, Hall M, Dew MA, Monk TH. Age Wise: Aging well by sleeping well. Journal of the American Geriatrics Society, 49:491, 2001.
  21. de Moor C, Sterner J, Hall M, Warneke C, Gilani Z, Amato R, Cohen L. A pilot study of the effects of expressive writing on psychological and behavioral adjustment in patients enrolled in a phase II trial of vaccine therapy for metastatic renal cell carcinoma. Health Psychology, 21: 615-9, 2002.
  22. Martire L, Hall M. Dementia caregiving: Recent research on negative health effects and the efficacy of caregiver interventions. CNS Spectrums, 7:791-6, 2002.
  23. Nofzinger EA, Buysse DJ, Miewald JM, Meltzer CC, Price JC, Sembrat RC, Ombao H, Reynolds CF, Monk TH, Hall M, Kupfer DJ, Moore RY. Human regional cerebral glucose metabolism during NREM sleep in relation to waking. Brain, 125:1105-15, 2002.
  24. Dew MA, Hoch CC, Buysse DJ, Monk T, Begley AE, Houck PR, Hall M, Kupfer DJ, Reynolds CF. Healthy older adults sleep predicts all-cause mortality at 4 to 19 years of follow-up. Psychosomatic Medicine, 65:63-74, 2003.
  25. *Germain A, Buysse DJ, Ombao H, Kupfer DJ, Hall M. Psychophysiological reactivity and coping styles influence the effects of acute stress exposure on REM sleep. Psychosomatic Medicine, 65:857-64, 2003.
  26. Redwine L, Dang J, Hall M, Irwin M. Disordered sleep, nocturnal cytokines and immunity in alcoholics. Psychosomatic Medicine, 65:75-85, 2003.
  27. Myaskovsky L, Dew MA, Switzer GE, Hall M, Kormos RL, Goycoolea MA, DiMartini AF, Manzetti JD, McCurry KR. Avoidant coping with health problems is related to poorer quality of life among lung transplant candidates. Progress in Transplantation, 13:183-92, 2003.
  28. Hall M, Vasko R, Buysse DJ, Ombao H, Chen Q, Cashmere JD, Kupfer DJ, Thayer JF. Acute stress affects heart rate variability during sleep. Psychosomatic Medicine, 66:56-62, 2004.
  29. Moul DE, Hall M, Pilkonis PA, Buysse DJ. Self-report measures of insomnia in adults: Rationales, choices, and needs. Sleep Medicine Reviews, 8:177-98, 2004.
  30. Germain A, Hall M, Krakow B, Shear MK, Buysse DJ. A brief sleep scale for posttraumatic stress disorder: Pittsburgh Sleep Quality Index addendum for PTSD. Journal of Anxiety Disorders, 19:233-44, 2004.
  31. Levitt H, Wood A, Moul DE, Hall M, Germain A, Kupfer DJ, Buysse DJ. A pilot study of daytime alertness and mood in insomnia patients using ecological momentary assessment. Behavioral Sleep Medicine, 2:113-31, 2004.
  32. Berger AM, Parker KP, Young-McCaughan S, Mallory GA, Barsevick AM, Beck SL, Carpenter JS, Carter PA, Farr LA, Hinds PS, Lee KA, Miaskowski C, Mock V, Payne JK, Hall M. Sleep/wake disturbances in people with cancer and their caregivers: State of the science. Oncology Nursing Forum, 32:E98-126, 2005.
  33. Thayer JF, Hall M, Sollers JJ, Fischer JE. Alcohol use, urinary cortisol, and heart rate variability in apparently healthy men: Evidence for impaired inhibitory control of the HPA axis in heavy drinkers. International Journal of Psychophysiology, 59:244-50, 2006.
  34. Germain A, Hall M, Shear MK, Nofzinger EA, Buysse DJ. Ecological study of sleep disruption in PTSD: A pilot study. Annals of the New York Academy of Sciences, 1071:438-41, 2006.
  35. Monk TH, Buysse DJ, Hall M, Nofzinger EA, Thompson W, Mazumdar SA, Reynolds CF. Age-related differences in the lifestyle regularity of seniors experiencing bereavement, care-giving, insomnia and advancement into old-old age. Chronobiology International, 23(4):831-41, 2006.
  36. Monk TH, Thompson WK, Buysse DJ, Hall M, Nofzinger EA, Reynolds CF. Sleep in healthy seniors: A diary study of the relation between bedtime and the amount sleep obtained. Journal of Sleep Research, 15:256-60, 2006.
  37. Nofzinger EA, Nissen C, Germain A, Moul D, Hall M, Price JC, Miewald JM, Buysse DJ. Regional cerebral metabolic correlates of WASO during NREM sleep in insomnia. Journal of Clinical Sleep Medicine, 2(3):316–22, 2006.
  38. Reynolds CF, Buysse DJ, Miller MD, Pollock BG, Hall M, Mazumdar S. Paroxetine treatment of primary insomnia in older adults. American Journal of Geriatric Psychiatry, 14(9):803-7, 2006.
  39. Germain A, Hall M, Shear MK, Nofzinger EA, Buysse DJ. Sleep disruption in PTSD: A pilot study with home-based polysomnography. Sleep and Biological Rhythms, 4: 286-89, 2006.
  40. Germain A, Shear MK, Hall M, Buysse DJ. Effects of a brief behavioral treatment for PTSD-related sleep disturbances: A pilot study. Behavior Research and Therapy, 45: 627-32, 2007.
  41. Jennings JR, Muldoon M, Hall M, Buysse DJ, Manuck SB. Self-reported sleep quality is associated with the metabolic syndrome. Sleep, 30(2):219-23, 2007.
  42. Hall M, Thayer JF, Germain A, Moul D, Vasko R, Puhl M, Miewald J, Buysse DJ. Psychological stress is associated with heightened physiological arousal during NREM sleep in primary insomnia. Behavioral Sleep Medicine, 5(3):178-93, 2007.
  43. *Okun ML, Hall M, Coussons-Read ME. Sleep disturbances increase IL-6 production during pregnancy: Implications for pregnancy complications. Reproductive Sciences, 14(6):560-7, 2007.
  44. Buysse DJ, Thompson W, Scott J, Franzen PL, Germain A, Hall M, Moul DE, Nofzinger EA, Kupfer DJ. Daytime symptoms in primary insomnia: A prospective analysis using ecological momentary assessment. Sleep Medicine, 8:198-208, 2007. PMCID: PMC1899354
  45. *Troxel WM, Robles T, Hall M, Buysse DJ. Marital quality and the marital bed: Examining the covariation between relationship quality and sleep. Sleep Medicine Reviews, 11(5):389-404, 2007. PMCID: PMC2644899
  46. *Troxel WM, Cyranowski JM, Hall M, Frank E, Buysse DJ. Attachment anxiety, relationship context, and sleep in women with recurrent major depression. Psychosomatic Medicine, 69: 692-9, 2007. PMCID: PMC2723846
  47. *Goldman SE, Stone KL, Ancoli-Israel S, Blackwell MA, Ewing SK, Boudreau R, Cauley JA, Hall M, Matthews KA, Newman AB. Poor sleep is associated with poorer physical performance and greater functional limitations in older women. Sleep, 30(10):1317-24, 2007. PMCID: PMC2266278
  48.  *Ranpuria R, Hall M, Chan CT, Unruh M. Heart rate variability (HRV) in kidney failure: measurement and consequences of reduced HRV. Nephrology Dialysis Transplantation, 23(2):444-9, 2008.
  49. Hall M, Buysse DJ, Nofzinger EA, Reynolds CF, Monk TH. Financial strain is a significant correlate of sleep continuity disturbances in late-life. Biological Psychology, 77: 217-22, 2008. PMCID: PMC2267650
  50. Hall M, Muldoon MF, Jennings JR, Buysse DJ, Flory JD, Manuck SB. Self-reported sleep duration is associated with the metabolic syndrome in mid-life adults. Sleep, 31(5):635-43, 2008. PMCID: PMC2398755
  51. *Mezick EJ, Matthews KA, Hall M, Strollo PJ, Buysse DJ, Kamarck TW, Owens JF, Reis SE. Influence of race and socioeconomic status on sleep: Pittsburgh SleepSCORE project. Psychosomatic Medicine, 70:410-6, 2008. PMCID: PMC2887747
  52. *Goldman SE, Hall M, Boudreau R, Matthews KA, Cauley JA, Ancoli-Israel S, Stone KL, Rubin SM, Satterfield S, Simonsick EM, Newman AB. Association between nighttime sleep and napping in older adults. Sleep, 31(5):733-40, 2008. PMCID: PMC2398743
  53. Kravitz HM, Zhao X, Bromberger JT, Gold EB, Hall M, Matthews KA, Sowers, MF. Sleep disturbance during the menopausal transition in a multi-ethnic community sample of women. Sleep, 31(7):979-90, 2008. PMCID: PMC2491500
  54. Matthews KA, Kamarck TW, Hall M, Strollo PJ, Owens JF, Buysse DJ, Lee L, Reis SE. Blood pressure dipping and sleep disturbance in african american and caucasian men and women. American Journal of Hypertension, 21(7):826-31, 2008. PMCID: PMC2890257
  55. Sowers MF, Zheng H, Kravitz HM, Matthews KA, Bromberger JT, Gold EB, Owens J, Consens F, Hall M. Sex steroid hormone profiles are related to sleep measures from polysomnography and the Pittsburgh Sleep Quality Index. Sleep, 31(10):1339-49, 2008. PMCID: PMC2572739
  56. *Goldman SE, Ancoli-Israel S, Boudreau R, Cauley JA, Hall M, Stone KL, Rubin SM, Satterfield S, Simonsick EM, Newman AB. Sleep problems and associated daytime fatigue in community-dwelling older individuals. Journal of Gerontology: Medical Sciences, 63A(10):1069-75, 2008.
  57. Buysse DJ, Hall M, Strollo PJ, Kamarck TW, Owens J, Lee L, Reis S, Matthews, KA. Relationships between the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and clinical/polysomnographic measures in a community sample. Journal of Clinical Sleep Medicine, 4(6):563-71, 2008. PMCID: PMC2603534
  58. Buysse DJ, Germain A, Hall M, Moul DE, Nofzinger EA, Begley A, Ehlers C, Thompson W, Kupfer DJ. EEG spectral analysis in primary insomnia: NREM period effects and sex differences. Sleep, 31(12):1673-82, 2008. PMCID: PMC2603490
  59. Hall M, Matthews K, Kravitz H, Gold E, Buysse DJ, Bromberger J, Owens J, Sowers MF. Race and financial strain are independent correlates of sleep in mid-life women: The SWAN Sleep Study. Sleep, 32(1):73-82, 2009. PMCID: PMC2625326
  60. *Troxel WM, Buysse DJ, Hall M, and Matthews KA. Marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women. Behavioral Sleep Medicine, 7:2-29, 2009. PMCID: PMC2654623
  61. *Okun ML, Hanusa B, Hall M, Wisner K. Sleep complaints in late pregnancy and the recurrence of postpartum depression. Behavioral Sleep Medicine, 7:106-17, 2009. PMCID: PMC2909658
  62. *Okun ML, Kravitz HM, Sowers MF, Moul DE, Buysse DJ, Hall M. Psychometric evaluation of the insomnia symptom questionnaire: A self-report measure to identify chronic insomnia. Journal of Clinical Sleep Medicine, 5:41-51, 2009. PMCID: PMC2637165
  63. *Okun ML, Coussons-Read ME, Hall M. Disturbed sleep is associated with increased C-reactive protein in young women. Brain, Behavior, and Immunity, 23:351-4, 2009. PMCID: PMC2909667
  64. *Okun ML, Roberts JM, Marsland AL, Hall M. How disturbed sleep may be a risk factor for adverse pregnancy outcomes. A Hypothesis. Ob-Gyn Survey, 64:273-80, 2009. PMCID: PMC2880322
  65. *Mezick EJ, Matthews KA, Hall M, Kamarck TW, Buysse DJ, Owens JF, Reis SE. Intra-individual variability in sleep duration and fragmentation: Associations with stress. Psychoneuroendocrinology, 34:1346-54, 2009. PMCID: 2743778
  66. *Prather AA, Marsland AL, Hall M, Neumann SA, Muldoon MF, Manuck SB. Normative variation in self-reported sleep quality and sleep debt is associated with stimulated pro-inflammatory cytokine production. Biological Psychology, 82(1):12-7, 2009. PMCID: PMC2727147
  67. Reynolds CF, Serody L, Okun ML, Hall M, Houck PR, Patrick S, Maurer J, Bensasi S, Mazumdar S, Bell B, Nebes RD, Miller MD, Dew MA, and Nofzinger EA. Protecting sleep, promoting health in later life: A randomized clinical trial. Psychosomatic Medicine, 72(2):178-86, 2010. PMCID: PMC2846078
  68. Troxel WM, Buysse DJ, Hall M, Kamarck T, Owens JF, Strollo PJ, Reis SE, Matthews KA. Social integration, social contacts, and nocturnal blood pressure in African Americans and Caucasians. Journal of Hypertension, 28: 265-71, 2010. PMCID: PMC2864490
  69. Vahtera J, Westerlund H, Hall M, Sjˆsten N, Kivim‰ki M, Salo P, Ferrie JE, Jokela M, Pentti J, Singh-Manoux A, Goldberg M, Zins M. Effect of retirement on sleep disturbances: The GAZEL prospective cohort study. Sleep, 31(11):1459-66, 2009. PMCID: PMC2768952
  70. Nabi H, Hall M, Koskenvuo M, Singh-Manoux A, Oksanen T, Suominen S, Kivim‰ki M, Vahtera J. Psychological and somatic symptoms of anxiety and risk of coronary heart disease: The HeSSup Prospective Cohort Study. Biological Psychiatry, 67:378-85, 2010. PMCID: PMC2963017
  71. *Okun ML, Krafty RT, Buysse DJ, Monk TH, Reynolds CF, Begley A, Hall M. What constitutes too long of a delay? Determining the cortisol awakening response (CAR) using self-report and PSG-assessed wake time. Psychoneuroendocrinology, 35(3):460-8, 2010. PMCID: PMC2823961
  72. *Mezick EJ, Matthews KA, Hall M, Kamarck TW, Strollo PJ, Buysse DJ, Owens JF, Reis SE. Low life purpose and high hostility are related to an attenuated decline in nocturnal blood pressure. Health Psychology, 29(2):196-204, 2010. PMCID: PMC2841295
  73. Troxel WM, Buysse DJ, Matthews KA, Kravitz HM, Bromberger JT, Sowers MF, Hall M. Marital/cohabitation status and history in relation to sleep in midlife women. Sleep, 33(7):862-3, 2010. PMCID: PMC199762
  74. Owens JF, Buysse DJ, Hall M, Kamarck TW, Lee L, Strollo PJ, Reis SE, Matthews KA. Napping, nighttime sleep, and cardiovascular risk factor in mid-life adults. Journal of Clinical Sleep Medicine, 6(4):330-5, 2010. PMCID: PMC2919622
  75. Matthews KA, Zheng H, Kravitz HM, Sowers M, Bromberger JT, Buysse DJ, Owens JF, Sanders M, and Hall M: Are inflammatory and coagulation biomarkers related to sleep characteristics in mid-life women? Study of Women’s Health across the Nation sleep study. Sleep, 33(12):1649-1655, 2010. PMCID: PMC2982735
  76. Nabi H, Shipley MJ, Vahtera J, Hall M, Korkeila J, Marmot MG, Kivimaki M, Singh-Manoux A: Effects of depressive symptoms and coronary heart disease and their interactive associations on mortality in middle-aged adults: the Whitehall II cohort study. Heart, 96(20):1645-1650, 2010. PMCID: PMC3151258
  77. *Roumelioti ME, Ranpuria R, Hall M, Hotchkiss JR, Chan CT, Unruh ML, Argyropoulos C. Abnormal nocturnal heart rate variability response among chronic kidney disease and dialysis patients during wakefulness and sleep. Nephrology Dialysis Transplantation, 25(11):3733-3741, 2010. PMCID: PMC2980993
  78. Salo P, Oksanen T, Sivertsen B, Hall M, Pentti J, Virtanen M, Vahtera J, Kivimaki M. Sleep disturbances as a predictor of cause-specific work disability and delayed return to work. Sleep, 33(10):1323-1331, 2010. PMCID: PMC2941418
  79. Troxel WM, Buysse DJ, Matthews KA, Kip KE, Strollo PJ, Hall M, Drumheller O, Reis SE. Sleep symptoms predict the development of the metabolic syndrome. Sleep, 33(12):1633-1640, 2010. PMCID: PMC2982733
  80. Troxel WM, Buysse DJ, Monk TH, Begley A, Hall M. Does social support differentially affect sleep in older adults with versus without insomnia? Journal of Psychosomatic Research, 69(5):459-466, 2010. PMCID: PMC2958100
  81. *Mezick EJ, Hall M, Matthews KA. Are sleep and depression independent or overlapping risk factors for cardiometabolic disease? Sleep Medicine Reviews, 15(1):51-63, 2011. PMCID: PMC2928398
  82. Okun ML, Reynolds CF, Buysse DJ, Monk TH, Mazumdar S, Begley A, Hall M. Sleep variability, health-related practices and inflammatory markers in a community dwelling sample of older adults. Psychosomatic Medicine, 73(2): 142-50, 2011. PMCID: PMC3106426
  83. Matthews KA, Strollo PJ, Hall M, Mezick EJ, Kamarck TW, Owens JF, Buysse DJ, Reis SE. Associations of Framingham risk score profile and coronary artery calcification with sleep characteristics in middle-aged men and women: Pittsburgh SleepSCORE study. Sleep, 34(6):711-716, 2011. PMCID: PMC3099492
  84. Kravitz HM, Avery E, Sowers MF, Bromberger JT, Owens JF, Matthews KA, Hall M, Zheng H, Gold EB, Buysse DJ. Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women: The SWAN Sleep Study. Sleep, 34(9): 1221-1232, 2011. PMCID: PMC3157664
  85. Krafty RT, Hall M, Guo W. Functional mixed effects spectral analysis. Biometrika, 98(3): 583-98, 2011.
  86.  Franzen PL, Gianaros PJ, Marsland AL, Hall M, Siegle GJ, Dahl RE, Buysse DJ: Cardiovascular reactivity to acute psychological stress following sleep deprivation. Psychosomatic Medicine, 73:679-682, 2011. PMCID: PMC3614084
  87. *Beatty DL, Hall M, Kamarck TA, Buysse DJ, Owens FJ, Reis SE, Mezick EJ, Strollo PJ, Matthews KA. Unfair treatment is associated with poor sleep in African American and Caucasian adults: Pittsburgh SleepSCORE Project. Health Psychology, 30(3): 351-9, 2011. PMCID: PMC3131074
  88. Campbell I, Bromberger J, Buysse D, Hall M, Hardin K, Kravitz HM, Matthews K, Rasor M, Utts J, Gold E. Evaluation of the association of menopausal status with delta and beta EEG activity during sleep. Sleep 34(11):1561-1568, 2011. PMCID: PMC3198211
  89. Zheng H, Sowers MF, Buysse DJ, Consens F, Kravitz HM, Matthews KA, Owens JF, Gold EB, Hall M. Sources of variability in epidemiological studies of sleep using repeated nights of in-home polysomnography: SWAN Sleep Study. Journal of Clinical Sleep Medicine 8(1): 86-97, 2012. PMCID: PMC3266336
  90. *Mezick EJ, Hall M, Matthews KA. Sleep duration and ambulatory blood pressure in black and white adolescents. Hypertension 59: 747-52, 2012. PMCID: PMC3314491
  91. Salo P, Vahtera J, Hall M, Rod NH, Virtanen M, Pentti J, Sjˆsten N, Oksanen T, Kivim‰ki M. Using repeated measures of sleep disturbances to predict future diagnosis-specific work disability: A cohort study. Sleep, 35(4):559-69, 2012. PMCID: PMC3296798
  92. Hall M, Okun ML, Sowers MF, Matthews KA, Kravitz HM, Hardin K, Buysse DJ, Bromberger JT, Owens JF, Karpov I, Sanders MH. Sleep is associated with the metabolic syndrome in a multi-ethnic cohort of mid-life women: The SWAN Sleep Study. Sleep,35(6):783-79, 2012. PMCID: PMC3353036
  93. *Prather AA, Hall M, Fury JM, Ross DC, Muldoon MF, Cohen S, Marsland A. Sleep and antibody response to Hepatitis B vaccination. Sleep, 35(8):1063-9, 2012. PMCID: PMC3397812
  94. *Israel B, Buysse DJ, Krafty RT, Begley A, Miewald J, Hall M. Short-term stability of sleep and heart rate variability in good sleepers and patients with insomnia: For some measures, one night is enough. Sleep, 35(9):1285-91, 2012. PMCID: PMC3413806
  95. *Kline CE, Sui X, Hall M, Youngstedt SD, Blair SN, Earnest CP, Church TS. Dose-response effects of exercise training on the subjective sleep quality of postmenopausal women: exploratory analyses of a randomised controlled trial. BMJ Open, 2(4), 2012. PMCID: PMC3400065
  96. Matthews KA, Dahl RE, Owens JF, Lee L, Hall M. Sleep duration and insulin resistance in healthy black and white adolescents. Sleep, 35(10):1353-58, 2012. PMCID: PMC23024433
  97. Boudebesse C, Leboyer M, Begley A, Wood A, Miewald J, Hall M, Frank E, Kupfer DJ, Germain A. Comparison of five actigraphy scoring methods in bipolar disorder: An objective/subjective spectrum of processing. Behavioral Sleep Medicine, 11:1-8, 2013. PMCID: PMC3869094
  98. Appelhans BM, Janssen I, Cursio JF, Matthews KA, Hall M, Gold EB, Burns JW, Kravitz HM. Sleep duration and weight changes in midlife women: The SWAN Sleep Study. Obesity, 21(1):77-84, 2013. PMCID: PMC3484178
  99. Krafty RT, Xiong S, Stoffer DS, Buysse DJ, Hall M. Enveloping spectral surfaces: covariate dependent spectral analysis of categorical time series. Journal of Time Series Analysis, 33(5):797-806, 2012. PMCID: PMC4002131
  100. *Irish LA, Dougall AL, Delahanty DL, Hall M. The impact of sleep complaints on physical health and immune outcomes in rescue workers: A 1-year prospective study. Psychosomatic Medicine, 75(2):196-201, 2013. PMCID: PMC3902641.
  101. *Levenson JC, Troxel WM, Begley A, Hall M, Germain A, Monk TH, Buysse DJ. A quantitative approach to distinguishing older adults with insomnia from good sleeper controls. Journal of Clinical Sleep Medicine, 9(2):125-131, 2013. PMCID: PMC3544379
  102. Insana SP, Hall M, Buysse DJ, Germain A. Validation of the Pittsburgh Sleep Quality Index Addendum for Posttraumatic Stress Disorder (PSQI-A) in U.S. Male Military Veterans. Journal of Traumatic Stress, 26(2):192-200, 2013. PMCID: PMC3746481
  103. Lewis TT, Troxel WM, Kravitz HM, Bromberger JT, Matthews KA, Hall M. Chronic exposure to everyday discrimination and sleep in a multi-ethnic sample of middle-aged women. Health Psychology, 32(7):810-19, 2013. PMCID: PMC3654016
  104. *Kline CE, Irish LA, Krafty RT, Sternfeld B, Kravitz HM, Buysse DJ, Bromberger JT, Dugan SA, Hall M. Consistently high sports/exercise activity is associated with better sleep quality, continuity and depth in midlife women: The SWAN Sleep Study. Sleep, 36(9):1279-88, 2013. PMCID: PMC3738036
  105. Krafty RT, Hall M. Canonical correlation analysis between time series and static outcomes, with application to the spectral analysis of heart rate variability. Annals of Applied Statistics, 7(1):570-87, 2013. PMCID: PMC4025993
  106. Low CA, Matthews KA, Hall M. Approach coping is associated with lower CRP among adolescents experiencing interpersonal stress. Psychosomatic Medicine, 75(6):449-52, 2013. PMCID: PMC3679199
  107. Hall M, Middleton K, Thayer JF, Lewis TT, Kline CE, Matthews KA, Kravitz HM, Krafty RT, Buysse DJ. Racial differences in heart rate variability during sleep in women: The Study of Women Across the Nation Sleep Study. Psychosomatic Medicine, 75:783-790, 2013. PMCID: PMC3902648
  108. Okun ML, Kline CE, Roberts JM, Wettlaufer B, Glover K, Hall M. Prevalence of sleep deficiency in early gestation and its associations with stress and depressive symptoms. Journal of Women’s Health, 22(12):1028-37, 2013. PMCID: PMC3852611
  109. *Mezick EJ, Matthews KA, Hall M, Richard JJ, Kamarck TW. Sleep duration and cardiovascular responses to stress in undergraduate men. Psychophysiology, 51(1): 88-96, 2014. PMCID: PMC3883723
  110. Matthews KA, Chang Y, Kravitz HM, Bromberger JT, Owens JF, Buysse DJ, Hall M. Sleep and risk for high blood pressure and hypertension in midlife women: The SWAN sleep study. Sleep Medicine, 15:203-208, 2014. PMCID: PMC3946296
  111. Krafty RT, Zhao M, Buysse DJ, Thayer JF, Hall M. Nonparametric spectral analysis of heart rate variability through penalized sum of squares. Statistics in Medicine, 33(8):1383-1394, 2014. PMCID: PMC3947457
  112. Tyagi S, Resnick NM, Perera S, Monk TH, Hall M, Buysse DJ. Behavioral treatment of insomnia: Also effective for nocturia. Journal of the American Geriatrics Society, 62(1):54-60, 2014. PMCID: PMC4055528
  113. Redline S, Sotres-Alvarez D, Loredo J, Hall M, Patel SR, Ramos A, Shah N, Ries A, Arens R, Barnhart J, Youngblood L, Zee P, Daviglus ML. Sleep disordered breathing in Hispanic/Latino individuals of diverse backgrounds. American Journal of Respiratory and Critical Care Medicine, 189(3):335-344, 2014. PMCID: PMC3977733
  114. Gunn, HE, Troxel WM, Hall M, Germain A, Buysse DJ. Interpersonal distress is associated with sleep and arousal in insomnia and good sleepers. Journal of Psychosomatic Research, 76(3):242-248, 2014. PMCID: PMC4018775
  115. *Irish LA, Kline CE, Rothenberger SD, Krafty RT, Buysse DJ, Kravitz HM, Bromberger JT, Zheng H, Hall M. A 24 hour approach to the study of health behaviors: Temporal dynamics of waking health behaviors and sleep. Annals of Behavioral Medicine, 47(2):189-197, 2014. PMCID: PMC3956705
  116. Tyagi S, Resnick NM, Perera S, Monk T, Hall M, Buysse DJ. Behavioral treatment of chronic insomnia in older adults: Does nocturia matter? Sleep, 37(4):681-687, 2014. PMCID: PMC4044748
  117. Hale L, Troxel WM, Kravitz HM, Hall M, Matthews KA. Acculturation and sleep among a multiethnic sample of women: The Study of Women’s Health Across the Nation (SWAN). Sleep, 37(2):309-317, 2014. PMCID: PMC3900614
  118. Matthews KA, Hall M, Dahl RE. Sleep duration, fragmentation and sleep quality among black and white adolescents: Should pediatricians be concerned? Pediatrics (in press). PMCID: PMC4006433
  119. Okun ML, Tolge M, Hall M. Low socioeconomic status negatively impacts sleep in pregnant women. Journal of Obstetric, Gynecologic, and Neonatal Nursing, 43(2):160-167, 2014. PMCID: PMC4084506
  120. Zheng H, Harlow SD, Kravitz HM, Bromberger J, Buysse DJ, Matthews KA, Gold EB, Owens JF, Hall M. Actigraphy-defined measures of sleep and movement across the menstrual cycle in midlife menstruating women: The SWAN Sleep Study. Menopause (in press).
  121. Gehrman PR, Hall M, Barilla H, Buysse DJ, Perlis M, Gooneratne NS, and Ross RJ: Stress reactivity in insomnia. Behavioral Sleep Medicine (in press).
  122. *Kay DB, Buysse DJ, Germain A, Hall M, Monk TH. Subjective-objective discrepancy in sleep among older adults: Associations with insomnia diagnosis and insomnia treatment. Journal of Sleep Research (in press).
  123. Soreca I, Buttenfield J, Hall M, Kupfer DJ. Screening for obstructive sleep apnea in patients with bipolar I disorder: comparison between subjective and objective measures. Bipolar Disorders (in press).
  124. Germain A, Richardson R, Stocker R, Mammen O, Hall M, Bramoweth A, Begley A, Rode N, Frank E, Haas G, Buysse DJ. Treatment for insomnia in combat-exposed OEF/OIF/OND military veterans: Preliminary randomized controlled trial. Behaviour Research and Therapy, 61:78-88, 2014. PMCID: In process
  125. *Kline CE, Irish LA, Owens JF, Bromberger JT, Gold EB, Kravitz HM, Sanders MH, Buysse DJ, Okun ML, Hall M. Sleep hygiene behaviors of midlife women with insomnia or sleep-disordered breathing: The SWAN Sleep Study. Journal of Women’s Health, 23(11):894-903, 2014. PMCID: In process
  126. Hall M, Cheng Y, Matthews KA. Sleep duration during the school week is associated with C-reactive protein risk groups in healthy adolescents. Sleep Medicine, 16(1):73-8, 2015.
  127. Hall M, Smagula SF, Boudreau RB, Ayonayon HN, Goldman SE, Harris TB, Naydeck BL, Rubin SM, Samuelsson LB, Satterfield S, Stone KL, Visser M, Newman AB. Association between short sleep duration and mortality is mediated by markers of inflammation in older adults: The Health, Aging and Body Composition Study. Sleep (in press).
  128. Kravitz HM, Zheng H, Bromberger JT, Buysse DJ, Owens J, Hall M. An actigraphy study of sleep and pain in midlife women: The SWAN sleep study. Menopause (in press).
  129. Troxel WM, Lee L, Hall M, Matthews KA. Single-parent family structure and sleep problems in black and white adolescents. Sleep Medicine, 15(2):255-261, 2014. PMCID: PMC3933955
  130. Frank E, Wallace ML, Hall M, Hasler B, Levenson JC, Janney C, Soreca I, Fleming MC, Buttenfield J, Kupfer DJ. An integrated risk reduction intervention can reduce body mass index in individuals being treated for bipolar disorder. Bipolar Disorders (in press).
  131. *Rothenberger SD, Krafty RT, Taylor BJ, Cribbet MR, Thayer JF, Buysse DJ, Kravitz HM, Buysse ED, Hall M. Time-varying correlations between slow wave sleep and heart rate variability in midlife women: The SWAN Sleep Study.  (in press).
  132. *Irish L, Kline CE, Gunn HE, Buysse DJ, Hall M. The role of sleep hygiene in promoting public health: A review of empirical evidence. Sleep Medicine Reviews (in press).
  133. Matthews KA, Hall M, Cousins J, Lee L. Getting a good night’s sleep in adolescence: Do strategies for coping with stress matter? Behavioral Sleep Medicine (in press).
  134. *Wilckens KA, Hall M, Nebes RD, Monk TH, Buysse DJ. Associations between sleep and cognitive performance before and after a behavioral intervention for chronic insomnia in older adults. Behavioral Sleep Medicine (in press).
  135. Prather AA, Janicki-Deverts D, Hall M, Cohen S. Sleep and susceptibility to the common cold. Sleep (in press).

Complete list of published work: http://www.ncbi.nlm.nih.gov/sites/myncbi/martica.hall.1/bibliography/43717039/public/?sort=date&direction=ascending

Christopher C. Imes, PhD, RN

Assistant Professor
Acute and Tertiary Care, School of Nursing

336 Victoria Building
3500 Victoria Street
Pittsburgh, PA 15261

E: imesc@pitt.edu

W: https://www.nursing.pitt.edu/person/christopher-c-imes 

T: 412-624-5872


Christopher E. Kline, Ph.D.

Assistant Professor
Department of Health and Physical Activity
32 Oak Hill Court, Room 227
Pittsburgh, PA  15261

E: chriskline@pitt.edu
T: 412-383-4027
F: 412-246-4045

Read More


  • BA, Sports Science, Malone College (Canton, Ohio), 2002
  • MS, Exercise Science, University of South Carolina (Columbia, SC), 2005
  • PhD, Exercise Science, University of South Carolina (Columbia, SC), 2011
  • Postdoctoral Fellowship, Translational Research Training in Sleep Medicine T32, University of Pittsburgh (Pittsburgh, PA), 2010-2013

Research Interests:

With undergraduate and graduate training in exercise science and postdoctoral training in sleep medicine, Dr. Kline is uniquely positioned to study the bidirectional relationship between physical activity and sleep. His research interests focus on the utility of exercise in the management of sleep disorders, the cardiometabolic consequences of poor sleep, and how exercise may reduce cardiometabolic risk via improvement of sleep quality. Currently, he is supported by a K23 Career Development Award through the NHLBI.

Current Research Funding:

  • K23 HL118318: A novel risk factor for cardiovascular disease: The insomnia-short sleep phenotype, 2014-2018 NIH RePORTER link  BAD LINK FOR NIH REPORTER

Selected Publications (Selected from 24 publications):

  1. Irish LA, Kline CE, Gunn HE, Buysse DJ, Hall MH. The role of sleep hygiene in promoting public health: a review of empirical evidence. Sleep Med Rev (in press). PubMed link
  2. Dishman RK, Sui X, Church TS, Kline CE, Youngstedt SD, Blair SN. Decline in cardiorespiratory fitness and odds of incident sleep complaints. Med Sci Sports Exerc (in press). PubMed link
  3. Kline CE. The bidirectional relationship between exercise and sleep: implications for exercise adherence and sleep improvement. Am J Lifestyle Med 2014;8:375-379. Article link
  4. Buman MP, Phillips B, Youngstedt SD, Kline CE, Hirshkowitz M. Does nighttime exercise really disturb sleep? Results from the 2013 National Sleep Foundation Sleep in America poll. Sleep Med 2014;15:755-761. PubMed link
  5. Iftikhar I, Kline CE, Youngstedt SD. The effects of exercise training on the severity of sleep apnea: a meta-analysis. Lung 2014;192:175-184. PubMed link
  6. Irish LA, Kline CE, Rothenberger SD, Krafty RT, Buysse DJ, Gold EB, Bromberger JT, Kravitz HM, Zheng H, Hall MH. A 24-hour approach to the study of health behaviors: temporal relationships between waking health behaviors and sleep. Ann Behav Med. 2014;47:189-197. PubMed link
  7. Hall M, Middelton K, Thayer JF, Lewis TT, Kline CE, Matthews KA, Kravitz HM, Krafty RT, Buysse DJ. Racial differences in heart rate variability during sleep in midlife women: the SWAN Sleep Study. Psychosom Med. 2013;75:783-790. PubMed Central link
  8. Kline CE, Irish LA, Krafty RT, Sternfeld B, Kravitz HM, Buysse DJ, Bromberger JT, Dugan SA, Hall MH. Consistently high sports/exercise activity is associated with better sleep quality, continuity and depth in midlife women: the SWAN Sleep Study. Sleep 2013;36:1279-1288. PubMed Central link
  9. Kline CE, Sui X, Hall MH, Youngstedt SD, Blair SN, Earnest CP, Church TS. Dose-response effects of exercise training on the subjective sleep quality of postmenopausal women: exploratory analyses of a randomised controlled trial. BMJ Open 2012;2:e001044. PubMed Central link
  10. Kline CE, Crowley EP, Ewing GB, Burch JB, Blair SN, Durstine JL, Davis JM, Youngstedt SD. Blunted heart rate recovery is improved following exercise training in overweight adults with obstructive sleep apnea. Int J Cardiol. 2013;167:1610-1615. PubMed Central link
  11. Kline CE, Ewing GB, Burch JB, Blair SN, Durstine JL, Davis JM, Youngstedt SD. Exercise training improves selected aspects of daytime functioning in adults with obstructive sleep apnea. J Clin Sleep Med. 2012;8:357-365. PubMed Central link
  12. Kline CE, Crowley EP, Ewing GB, Blair SN, Durstine JL, Davis JM, Burch JB, Youngstedt SD. The effect of exercise training on obstructive sleep apnea and sleep quality: a randomized controlled trial. Sleep. 2011;34:1631-1640. PubMed Central link
  13. Youngstedt SD, Kline CE, Zielinski MR, Kripke DF, Devlin TM, Bogan RK, Wilcox S, Hardin JW. Tolerance of chronic moderate sleep restriction in older long sleepers. Sleep. 2009;32:1467-1479. PubMed Central link
  14. Zielinski MR, Kline CE, Kripke DF, Bogan RK, Youngstedt SD. No effect of chronic moderate sleep restriction on glucose tolerance in older long sleepers. J Sleep Res. 2008;17:412-419. PubMed Central link
  15. Kline CE, Durstine JL, Davis JM, Moore TA, Devlin TM, Zielinski MR, Youngstedt SD. Circadian variation in swim performance. J Appl Physiol. 2007;102:641-649. PubMed link
  16. Youngstedt SD, Kline CE. Epidemiology of exercise and sleep. Sleep Biol Rhythms. 2006;4:217-221. PubMed Central link

PubMed Author Search

Google Scholar Profile

Erek M. Lam, MD

Clinical Assistant Professor
Department of Neurology
12690 Perry Hwy, Suite 170
Wexford, PA 15090

E: lamem@upmc.edu

W: www.upmc.com/locations/hospitals/passavant/services/neurology

T: 412-367-1003

F: 412-367-2725

Jessica Levenson, PhD

Assistant Professor
Department of Psychiatry
3811 O’Hara Street, Room E-1119
Pittsburgh, PA 15213

E: levensonjc@upmc.edu
T: 412-647-7937
T: 412-246-6413
F: 412-246-5300

Read More


  • BA, Psychology with Honors, Brandeis University (Waltham, MA), 2004
  • MS, Clinical Psychology, University of Pittsburgh (Pittsburgh, PA), 2008
  • Clinical Psychology Internship, University of Wisconsin School of Medicine (Madison, WI), 2013
  • PhD, Clinical Psychology, University of Pittsburgh (Pittsburgh, PA), 2013
  • Postdoctoral Fellowship, Sleep Medicine T32, University of Pittsburgh, 2013-2016

Research Interests:

Dr. Levenson’s research interests focus on designing and evaluating interventions for adolescents that enhance sleep health specifically to promote mental and physical health broadly. She uses qualitative and quantitative approaches to developing stakeholder-informed interventions that are likely to be effective, adopted, and implemented.  Dr. Levenson specifically focuses on using technology to deliver innovative interventions that increase access, engagement, and cost-effectiveness. Her work also explores the role of disturbed sleep in the onset and course of depression and bipolar disorder. Dr. Levenson is a licensed clinical psychologist who works with adolescents and adults. Her clinical interests focus primarily on the treatment of mood disorders and sleep disorders.

Current Research Funding:

  • Focused Projects Award, American Sleep Medicine Foundation
  • Bridge to Success Award, American Sleep Medicine Foundation

Selected Publications:

  1. Levenson, J.C., Kay, D.B., Buysse, D.J. (2015). The pathophysiology of insomnia. CHEST. 147, 4, 1179-1192. PMID: 25846534 PMCID: PMC4388122
  2. Levenson, J.C., Wallace, M.L., Anderson, B.P., Kupfer, D.J., Frank, E. (2015). Social Rhythm Disrupting Events Increase the Risk of Recurrence among Individuals with Bipolar Disorder. Bipolar Disorders, 17(8), 869-879. PMID: 26614534 PMCID: PMC4702482
  3. Levenson, J.C., Miller, E., Hafer, B., Reidell, M.F., Buysse, D.J., Franzen, P.L. (2016). Pilot study of a sleep health promotion program among college students. Sleep Health, 2(2), 167-174. PMID: 27525300, PMCID: PMC4978431
  4. Parthasarathy, S., Buysse, D.J., Carskadon, M., Jean-Louis, G., Owens, J., Bramoweth, A., Combs, D., Hart, C., Hasler, B., Honaker, S.M., Hickam, D., Hertenstein, E., Kuna, S., Kushida, C., Levenson, J.C.,…Stoney, K. (2016). Implementation of sleep and circadian science: recommendations from the Sleep Research Society and National Institutes of Health workshop. SLEEP, 39(12):2061-2075. PMID: 27748248 PMCID: PMC5103795
  5. Levenson, J.C., Soehner, A., Rooks, B.T., Merranko, J., Goldstein, T.R., Axelson, D.A., Goldstein, B.I., Brent, D.A., Diler, R., Hafeman, D., Hickey, M.B., Monk, K., Sakolsky, D., Kupfer, D.J., Birmaher, B. (2017).  Sleep phenotypes among offspring of bipolar parents and community controls: a latent transition analysis and association with conversion to bipolar disorder. Journal of Affective Disorders, 215, 30-36. PMID: 28315578 DOI: 10.1016/j.jad.2017.03.011
  6. Levenson, J.C., Rollman, B.L., Ritterband, L., Strollo, P.J., Smith, K.J., Yabes, J.G., Moore, C.G., Harvey, A.G., Buysse, D.J. (2017). Hypertension with Unsatisfactory Sleep Health (HUSH): Study Protocol for a Randomized Controlled Trial. Trials, 18(1). PMID: 28587609 PMCID: PMC5461741
  7. Levenson, J.C., Shensa, A., Sidani, J.E., Colditz, J.B., Primack, B.A. (2017). Social Media Use before Bed and Sleep Disturbance among Young Adults in the United States: A Nationally-Representative Study. SLEEP, 40(9). PMID: 28934521 DOI: 10.1093/sleep/zsx113
  8. Goldstein, T.R., Merranko, J., Krantz, M. Garcia, M., Franzen, P.L., Levenson, J.C., Birmaher, B., Frank, E. (2018). Early Intervention for Adolescents At-Risk for Bipolar Disorder: A Pilot Randomized Trial of Interpersonal and Social Rhythm Therapy. Journal of Affective Disorders, 235, 348-356. PMID: 29665518, PMCID: PMC5951768, DOI: 10.1016/j.jad2018.04.049
  9. Soehner A.M., Bertocci M.A., Levenson J.C., Goldstein T.R., Rooks B., Merranko J., Hafeman D., Diler R., Axelson D., Goldstein B.I. , Hickey M.B., Monk K.M., Phillips M.L., Birmaher B. (In Press). Longitudinal relationships between sleep patterns and psychiatric symptom severity in high-risk and community control youth. Journal of American Academy of Child and Adolescent Psychiatry.

Faith S Luyster, PhD

Assistant Professor
School of Nursing
3500 Victoria Street, Room 415
Pittsburgh, PA 15261


W: https://www.nursing.pitt.edu/person/faith-s-luyster 
T: 412-624-7910


Colleen A. McClung, PhD

Professor of Psychiatry and Clinical and Translational Science
450 Technology Drive, Suite 223
Pittsburgh, PA 15219

E: mcclungca@upmc.edu
W: http://mcclung.pitt.edu/
T: 412-624-5547

Assistant: Michele Nace
Assistant Phone: 412-624-5546
Assistant Email: nacem@upmc.edu


Sanjay R. Patel, MD, MS

Professor of Medicine, Epidemiology, and Clinical and Translational Science
Director, Center for Sleep and Cardiovascular Outcomes Research, UPMC

3609 Forbes Avenue, 2nd Floor, Room 108
Pittsburgh, PA 15213

E: patelsr2@upmc.edu

W: https://profiles.dom.pitt.edu/PACCM/faculty_info.aspx/Patel6607

T: 412-383-0607


Assistant: Cynthia Hatfield
Assistant Phone: 412-647-2461
Assistant Email: hatfieldca2@upmc.edu


Kathryn A. Roecklein, Ph.D.

Assistant Professor
Department of  Psychology
4123 Sennott Square
University of Pittsburgh

E: kroeck@pitt.edu
T: 802 881-8895
W: www.roecklein.pitt.edu


Stephen Smagula, PhD

Assistant Professor
Department of Psychiatry
3811 O’Hara Street, Room E-1121
Pittsburgh, PA 15213

E: sfs26@pitt.edu
T: 412-246-6413
F: 412-246-5300

Read More


  • BS, Neuroscience, Lafayette College (Easton, PA), 2009
  • MS, Neuroscience and Education, Teachers College Columbia University (New York, NY), 2010
  • PhD, Epidemiology, University of Pittsburgh Graduate School of Public Health (Pittsburgh, PA), 2014
  • Postdoctoral Fellowship, Late-Life  T32, University of Pittsburgh, 2015-2017
  • Postdoctoral Fellowship, Sleep Medicine T32, University of Pittsburgh, 2017

Research Interests:

Dr. Smagula’s research focuses on understanding how 24-hour sleep-wake patterns influence the mechanisms underlying late-life depression. His past work investigated phenotypic heterogeneity in major depressive disorder among older adults, and in particular, the neurobiological and clinical determinants of response to pharmacological therapy.  He has also contributed to literature on how sleep changes with aging. Dr. Smagula is currently investigating the risk architecture of depression among family caregivers of people with dementia.


Privacy Policy


Selected Publications:

  1. Smagula SF, Beach S, Rosso AL, Newman AB, Schulz R. (in press). Brain structural markers and caregiving characteristics as interacting correlates of caregiving strain. American Journal of Geriatric Psychiatry.
  2. Smagula SF, Krafty RT, Taylor BJ, Martire LM, Schulz R, & Hall MH. (in press). Rest-activity rhythm and sleep characteristics associated with depression symptom severity in strained dementia caregivers. Journal of Sleep Research.
  3. Smagula SF, Ancoli-Israel S, Blackwell T, Boudreau R, Stefanick M, Paudel M, Stone KL, Cauley JA. (2015). Circadian rest-activity rhythms predict future increases in depressive symptoms among community-dwelling older men. American Journal of Geriatric Psychiatry, 23(5): 495-505. doi: 10.1016/j.jagp.2014.06.007.
  4. Smagula SF, Stone KL, Fabio A, Cauley JA. (2016). Risk factors for sleep disturbances in older adults: evidence from prospective studies. Sleep Medicine Reviews, 25:21-30. doi: http://dx.doi.org/10.1016/j.smrv.2015.01.003.
  5. Karim HT, Andreescu C, Tudorascu D, Smagula SF, Butters MA, Karp JF, Reynolds CF, Aizenstein HJ. (2017). Intrinsic functional connectivity in late-life depression: trajectories over the course of pharmacotherapy in remitters and non-remitters. Molecular Psychiatry, 22:450-457.
  6. Kaneriya SH*, Robbins-Welty GA*, Smagula SF*, Karp JF, Butters MA, Lenze EJ, Mulsant BH, Blumberger D,  Anderson SJ, Dew MA, Lotrich FE,  Aizenstein HJ, Diniz BS, Reynolds CF. (2016). Predictors and moderators of remission with aripiprazole augmentation in treatment-resistant late-life depression. JAMA Psychiatry, 73(4):329-36.*denotes shared first-authorship with medical student mentees;
  7. Smagula SF, Butters MA, Anderson SJ, Lenze EK, Dew MA, Mulsant, BH, Lotrich FE, Aizenstein H, Reynolds CF. (2015). Antidepressant response trajectories and associated clinical prognostic factors in late-life depression. JAMA Psychiatry, 72(10):1021-1028. doi: 10.1001/jamapsychiatry .2015.1324.

Adriane Soehner, PhD
Assistant Professor
Department of Psychiatry
3811 O’Hara Street, Room E-1130
Pittsburgh, PA 15213

T: 412-246-5971
F: 412-246-5300

Loeffler Rm 304
T: 412-383-8200

E: soehneram2@upmc.edu

Read More


  • BS, Biological Sciences and Psychology, Carnegie Mellon University (Pittsburgh, PA), 2008
  • MA, Psychology, University of California, Berkeley (Berkeley, CA), 2010
  • PhD, Clinical Science, University of California, Berkeley (Berkeley, CA), 2014
  • APA-Accredited Clinical Psychology Internship, Western Psychiatric Institute & Clinic (Pittsburgh, PA), 2013-2014
  • Postdoctoral Fellowship, Clinical Research Training for Psychologists T32, University of Pittsburgh (Pittsburgh, PA), 2014-2016
  • Postdoctoral Fellowship, Translational Research Training in Sleep Medicine T32, University of Pittsburgh (Pittsburgh, PA), 2016

Current Research Funding:

  • Vulnerability to Bipolar Disorder in Adolescence: Interactions Among Sleep Variability, Familial Risk, and Reward-Control Processes, National Institute of Mental Health [K01MH111953], 2016-2021, NIH Reporter

  • Rapid Antidepressant Effects of Selective Slow Wave Sleep Deprivation in Depressed Youth, Klingenstein Third Generation Foundation, 2018-2020

  • Sleep Health Across the Lifespan: Developing the Pittsburgh Lifespan Sleep Databank, University of Pittsburgh Clinical & Translational Science Institute, 2019-2020

Research Interests:

Dr. Soehner investigates the role of sleep in the development of brain networks and mood disorders from adolescence in adulthood.  Her research combines functional neuroimaging with naturalistic assessment and therapeutic manipulation of sleep in youth and young adults.  


Selected Publications:

  1. Soehner AM, Bertocci MA, Levenson JC, Goldstein TR, Rooks B, Merranko J, Hafeman D, Diler R, Axelson D, Goldstein BI, et al. Longitudinal Associations Between Sleep Patterns and Psychiatric Symptom Severity in High-Risk and Community Comparison Youth. J Am Acad Child Adolesc Psychiatry. 2019 Mar 6.
  2. Soehner AM, Goldstein TR, Gratzmiller SM, Phillips ML, Franzen PL. Cognitive control under stressful conditions in transitional age youth with bipolar disorder: Diagnostic and sleep-related differences in fronto-limbic activation patterns. Bipolar Disord. 2018 May;20(3):238-247.
  3. Soehner AM, Kaplan KA, Saletin JM, Talbot LS, Hairston IS, Gruber J, Eidelman P, Walker MP, Harvey AG. You’ll feel better in the morning: slow wave activity and overnight mood regulation in interepisode bipolar disorder. Psychol Med. 2018 Jan;48(2):249-260.
  4. Soehner AM, Bertocci MA, Manelis A, Bebko G, Ladouceur CD, Graur S, Monk K, Bonar LK, Hickey MB, Axelson D, Goldstein BI, Goldstein TR, Birmaher B, Phillips ML. Preliminary investigation of the relationships between sleep duration, reward circuitry function, and mood dysregulation in youth offspring of parents with bipolar disorder. J Affect Disord. 2016 Nov 15;205:144-153.
  5. Harvey AG, Soehner AM, Kaplan KA, Hein K, Lee J, Kanady J, Li D, Rabe-Hesketh S, Ketter TA, Neylan TC, Buysse DJ. Treating insomnia improves mood state, sleep, and functioning in bipolar disorder: a pilot randomized controlled trial. J Consult Clin Psychol. 2015 Jun;83(3):564-77.
  6. Soehner AM, Harvey AG. Prevalence and functional consequences of severe insomnia symptoms in mood and anxiety disorders: results from a nationally representative sample. Sleep. 2012 Oct 1;35(10):1367-75
  7. Soehner AM, Kaplan KA, Harvey AG. Insomnia comorbid to severe psychiatric illness. Sleep Med Clin. 2013 Sep;8(3):361-371.
  8. Harvey AG, Murray G, Chandler RA, Soehner A. Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms. Clin Psychol Rev. 2011 Mar;31(2):225-35.

Ryan J Soose, MD

Associate Professor
Department of Otolaryngology
UPMC Mercy, Suite 2100
1400 Locust Street
Pittsburgh, PA 15219

E: sooserj@upmc.edu

W: www.upmc.com/sleep

T: 412-232-3687
F: 412-232-3713

Assistant: Nancy Szablewski
Assistant Phone: 412-232-8989
Assistant Email: szablewskina@upmc.edu

Sarah T. Stahl, PhD

Assistant Professor
Department of Psychiatry
3811 O’Hara Street, 754 BT
Pittsburgh PA, 15213

E: Sarah.Stahl@pitt.edu

T: 412-246-6003
F: 412-246-5991

Patrick J Strollo, Jr., MD 
Professor of Medicine and Clinical and Translational Science 
UPMC Montefiore
Suite S639.11 
3459 Fifth Avenue 

Pittsburgh, PA 15213

E: strollopj@upmc.edu

T: 412-692-2892
F: 412-692-2260

Assistant name: Amy Wesolowski
Assistant Phone: 412-802-8594
Assistant Email: wesolowskiam@upmc.edu

Rebecca C Thurston, PhD

Professor of Psychiatry, Psychology, Epidemiology, and Clinical and Translational Science

201 North Craig St, Ste 206
Pittsburgh PA 15213

E: thurstonrc@upmc.edu

W: thurstonlab.pitt.edu

T: 412-648-9087

Assistant name: Carey Mittermeier, MID, MPH
Assistant Phone: 412-648-9270
Assistant Email: mittermeiercl@upmc.edu

Meredith Wallace, Ph.D.

Associate Professor
Department of Psychiatry
3811 O’Hara Street, Room E-1130
Pittsburgh, PA 15213

E: lotzmj@upmc.edu
T: 412-246-6413
F: 412-246-5300

Read More


  • BA, Psychology and Statistics, St. Olaf College (Northfield, MN), 2004
  • PhD, Biostatistics, University of Pittsburgh (Pittsburgh, PA), 2009
  • Postdoctoral Fellowship, Psychiatry, University of Pittsburgh (Pittsburgh, PA), 2009-2011
  • Postdoctoral Fellowship, Statistics, University of Pittsburgh (Pittsburgh, PA), 2011-2013

Research Interests:

Dr. Wallace is a biostatistician with a research emphasis on the development of statistical methods to enhance personalized medicine, including machine learning algorithms, clustering, and moderators.  She primarily applies these methods to advance sleep, mood, and anxiety disorders research. Through her NIMH K01 (MH096944) focused on clustering, she developed methods to reveal homogenous subgroups based on high-dimensional multi-modal sleep data and applied clustering to define heterogeneity in cross-diagnostic samples.  Following her K01, she received R01 support from the NIA (R01NIA056331) to develop a large, harmonized database including multiple sleep cohorts of older adults. With these data, she applies machine learning and her cutting-edge multivariable clustering approaches to study the association between multivariable sleep health and mortality in older adults.  Dr. Wallace has also been integral in demonstrating and applying statistical methods for optimal combined moderators that utilize machine learning to characterize subgroups of individuals for whom one treatment or experimental condition may have a desirable or undesirable effect relative to the other.

Current Research Funding:

  • R21 DA045137 (Co-I): Cognitive Remediation and Transcranial Direct Current Stimulation to Aid Smokers with Schizophrenia, 2017-2019.
  • R01 AA025626 (Co-I): Proximal Prospective Associations between Circadian Alignment, Reward Function and Alcohol Use in Adolescents, 2017-2022.
  • R01 HL135218 (Co-I): Postpartum Weight Retention and Cardiometabolic Disparities: The Effects of Contextual, Psychosocial, and Behavioral Factors, 2017-2022.
  • R21 MH112770 (Co-I): Testing the Causal Role of Orbitofrontal Cortex in Human Compulsive Behavior: A Non-invasive Brain Stimulation Study, 2017-2019.
  • Staunton Foundation (Co-I): School Avoidance and Virtual School Consultation (VSC), 2017-2023.
  • R01 AG056331 (PI): Sleep Health Profiles and Mortality Risk in Older Adults: A Multi-Cohort Application of Novel Statistical Methods, 2017-2020.
  • R03 MH116478 (Co-I): Cutting-Edge Clustering of Emotional Reactivity to Reveal Novel Anxiety Subtypes, 2018-2020.
  • R01 MH113827 (Co-I): Characterize Differences in Sleep Spindles between Clinical High Risk and Healthy Controls Longitudinally , 2018-2022.
  • R01 DA044143 (Co-I): Delayed Sleep Phase and Risk for Adolescent Substance Use, 2018-2023.
  • R01 MH116005 (Co-I): Sleep-Dependent Negative Overgeneralization in Peripubertal Anxiety, 2018-2023.
  • R01 AA025617 (Co-I): Understanding Differences in Risk for Alcohol Problems between Black and White Drinkers: Integrating Alcohol Response, Stress, and Drinking Motives, 2018-2023.
  • R01 AA026249 (Co-I): Positive and Negative Reinforcement Pathways Underlying Sleep and Alcohol Use Associations, 2018-2023.

Selected Publications:

  1. Wallace ML, Frank E, Kraemer HC.   A novel approach for developing and interpreting treatment moderator profiles. JAMA Psychiatry. 2013 Nov;70(11):1241-7. doi: 10.1001/jamapsychiatry.2013.1960. PubMed PMID: 24048258.
  2. Wallace ML. Time-dependent tree-structured survival analysis with unbiased variable selection through permutation tests. Stat Med. 2014 Nov 30;33(27):4790-804. doi: 10.1002/sim.6261. PubMed PMID: 25043382.
  3. Wallace ML, Simsek B, Kupfer DJ, Swartz HA, Fagiolini A, Frank E. An approach to revealing clinically relevant subgroups across the mood spectrum. J Affect Disord. 2016 Oct; 203: 265-74.  doi: 10.1016/j.jad.2016.06.019. PubMed PMID: 27314873.
  4. Wallace ML, McMakin DL, Tan PZ, Rosen D, Forbes EE, Ladouceur CD, Ryan ND, Siegle GJ, Dahl RE, Kendall PC, Mannarino A (2017).  The role of day-to-day emotions, sleep, and social interactions in pediatric anxiety treatment. Behav Res Ther. 2017 Mar;90:87-95.  doi: 10.1016/j.brat.2016.12.012. PubMed PMID: 28013054.
  5. Wallace ML, Stone K, Smagula SF, Hall MH Simsek B, Kado D, Redline S, Vo Tien, Buysse DJ, Osteoporotic Fractures in Men (MrOS) Study Research Group.  Which sleep health characteristics predict all-cause mortality in older men? An application of flexible multivariable methods. SLEEP. 2018 Jan 1; 41(1). doi: 10.1093/sleep/zsx189. PubMed PMID: 29165696.
  6. Wallace ML, Buysse DJ, Germain A, Hall MH, Iyengar S. Variable selection for skewed model-based clustering: Application to the identification of novel sleep phenotypes.  J Am Stat Assoc. 2018; 113(521): 95-110.  doi: 10.1080/01621459.2017.1330202
  7. Wallace ML, Banihashemi L, O’Donnell C, Nimgaonkar VL, Kodavali C, McNamee R, Germain A. Using optimal combined moderators to define heterogeneity in neural responses to randomized conditions: Application to the effect of sleep loss on fear learning.  NeuroImage 2018 Nov 1;181:718-727. doi:10.1016/j.neuroimage.2018.07.051 PubMed PMID: 29480752.
  8. Wallace ML, Buysse DJ, Redline S, Stone K, Ensrud K, Leng Y, Ancoli-Israel S, Hall MH. Multidimensional sleep and mortality in older adults: A machine-learning comparison with other risk factors. The Journals of Gerontology, Series A, Epub Ahead of Print. doi: 10.1093/gerona/glz044.

PubMed Profile


Kristine A. Wilckens, Ph.D.

Assistant Professor
Department of Psychiatry
3811 O’Hara Street, Room E-1124
Pittsburgh, PA 15213

E: krw37@pitt.edu
T: 412-586-9434
F: 412-246-5300

Read More


  • BA, Psychology, Rutgers University, Douglass College (New Brunswick, NJ), 2006
  • MA, Psychology, New York University (New York, NY), 2008
  • PhD, Cognitive Psychology, University of Pittsburgh (Pittsburgh, PA), 2012
  • Postdoctoral Fellowship, Geriatric Psychiatry T32, University of Pittsburgh (Pittsburgh, PA), 2012-2015

Research Interests:

Dr. Wilckens investigates the role of sleep in promoting brain health and cognitive fitness. Her research program focuses on 1) neural processes during sleep that restore cognitive function and mitigate neurodegeneration and 2) sleep enhancement interventions that improve functioning of brain networks and mitigate cognitive impairments and progression of Alzheimer’s disease. Sleep enhancement methods include behavioral interventions and laboratory-based techniques such as transcranial magnetic stimulation.

Current Research Funding:

  • Alzheimer’s Disease Research Center Donations Program, University of Pittsburgh

Selected Publications:

1. Wilckens, K.A., Tudorascu, D.L., Snitz, B.E., Price, J.C., Aizenstein H.J., Lopez, O.L., Erickson, K.I., Lopresti, B.J., Laymon, C.M., Minhas, D., Mathis, C.A., Buysse, D.J., Klunk, W.E., Cohen, A.D. Sleep efficiency moderates the relationship between beta amyloid and memory retention in older adults. Neurobiology of Aging. 2018. 71, 142-148.

2. Wilckens, K.A., Ferrarelli, F., Walker, M.P., Buysse, D.J. Slow-wave sleep enhancement to improve cognition. Trends in Neurosciences. 2018; 41(7), 470-482.

3. Wilckens, K.A., Hall, M., Erickson, K.I., Germain, A. Nimgaonkar, V.L., Monk, T.H., Buysse, D.J. Task-switching in older adults with and without insomnia. Sleep Medicine. 2017; 30, 113-120. PMCID: PMC5321623

4. Wilckens, K.A., Erickson, K.I., Wheeler, M.E. Physical activity and executive function: a mediating role of efficient sleep. Behavioral Sleep Medicine. 2016; 1-18. PMCID: PMC5466488.

5. Kay, D.B., Karim, H.T., Soehner, A., Hasler, B.P., Wilckens, K.A., James, J.A., Aizenstein, H.J., Price, J.C., Rosario, B.L., Kupfer, D.J., Germain, A., Hall, M.H., Franzen, P.L., Nofzinger, E.A., Buysse, D.J. Sleep-wake differences in relative regional cerebral metabolic rate for glucose among patients with insomnia compared with good sleepers. Sleep. 2016. 2016. 1(39), 1779-1794. PMCID: PMC5020360

6. Wilckens, K.A., Aizenstein, H.J., Nofzinger, E.A, James, J.A., Hasler, B.P., Rosario-Rivera, B.L., Franzen, P., Germain, A., Hall, M.H., Kupfer, D.J., Price, J.C., Siegle, G.J., Buysse, D.J. The Role of non-rapid eye movement slow-wave activity in prefrontal metabolism across young and middle age adults. Journal of Sleep Research. 2016; 25(3), 296-306. PMCID: PMC5354539

7. Wilckens, K.A., Nebes, R., Hall, M., Monk, T., Buysse, D.J. Changes in Cognitive Performance are Associated with Changes in Sleep in Older Adults with Insomnia. Behavioral Sleep Medicine. 2016; 1-16. PMCID: PMC4775463

8. Wilckens, K.A., Woo, S.G., Kirk, A.R., Erickson, K.I., Wheeler, M.E. The role of sleep continuity and total sleep time in executive function across the adult lifespan. Psychology & Aging. 2014; 29(3). PMC4369772

9. Wilckens, K.A., Woo, S.G., Erickson, K.I., Wheeler, M.E. Sleep continuity and total sleep time are associated with task-switching and preparation in young and older adults. Journal of Sleep Research. 2014; 23 (5). PMC4177284

10. Wilckens K.A., Erickson KI, Wheeler ME. Age-related decline in controlled retrieval: The role of the PFC and sleep. Neural Plasticity. 2012. PMC3434414

PubMed Author Search

Google Scholar Profile