Brant P. Hasler, Ph.D.

Assistant Professor

Department of Psychiatry

3811 O'Hara Street, Room E-1121

Pittsburgh, PA 15213

E: haslerbp@upmc.edu

T: 412-246-6413

F: 412-246-5300

Current trainees:

     •     Thomas Mike, BA; Christopher Mantick

     •     Accepting trainees: Yes


     •     BA, Neuroscience & Behavior, Wesleyan University (Middletown, CT), 1994

     •     MS, Clinical Psychology, University of Arizona (Tucson, AZ), 2005

     •     PhD, Clinical Psychology, University of Arizona (Tucson, AZ), 2009

     •     Postdoctoral Fellowship, Translational Research Training in Sleep Medicine (T32), University of Pittsburgh (Pittsburgh, PA),


Research Interests:

Dr. Hasler’s research focuses on the role of sleep and circadian rhythms in regulating affect and motivation, particularly as relevant to affective disorders and substance abuse. In addition to his research program, Dr. Hasler is actively engaged in research mentorship and clinical supervision, as well as direct clinical practice, and is the Co-Director of our accredited Behavioral Sleep Medicine training fellowship.

Current Research Funding:

     •     K01 DA032557 (Hasler): Circadian Misalignment and Reward Function: A Novel Pathway to Substance Use, 2012-2017.

        Role: PI. NIH RePORTER link

     •     AA021690 (Clark): National Consortium on Alcohol and NeuroDevelopment in Adolescence, 2012-2017. Role: Co-I

        NIH RePORTER link     

     •     R21 MH102412 (Buysse): Dimensional Sleep Disturbance in Relation to Positive/Negative Affect Systems, 2014-2016. Role:

       Co-I NIH RePORTER link

     •     R21 AA023209 (Hasler): Circadian Alignment, Reward Function, and Alcohol Use During Late Adolescence, 2014-2016. Role:

        PI NIH RePORTER link

     •     R01 MH103313 (Roecklein): Melanopsin Photosensitivity and Psychopathology, 2014-2019. Role: Co-I NIH RePORTER link

Selected Publications:

     1.     Miller MA, Rothenberger SD, Hasler BP, Donofry SD, Wong PM, Manuck SB, Kamarck KA, Roecklein KA. Chronotype predicts

        positive affect rhythms measured by ecological momentary assessment. Chronobiology International. (in press)

     2.     Gunn HE, Buysse DJ, Hasler BP, Begley A, Troxel WM. Sleep concordance in couples is associated with relationship

        characteristics. Sleep. (in press)

     3.     Frank E, Wallace ML, Hall M, Hasler B, Levenson L, Janney CA, Soreca I, Fleming MC, Buttenfield J, Ritchey FC, Kupfer DJ. An

        integrated risk reduction intervention can reduce body mass index in individuals being treated for bipolar disorder. Bipolar

        Disorders. (in press) (PMCID: in process)

     4.     Hasler BP, Forbes EE, Franzen PL. Time-of-day differences and short-term stability of the neural response to monetary reward:

        A pilot study. Psychiatry Research: Neuroimaging, 224, 22-27, 2014. PMCID: PMC4157087

     5.     Hasler BP, Soehner AM, Clark DB. Sleep and circadian contributions to adolescent alcohol use disorder. Alcohol. (in press)

        (PMCID: in process)

     6.     Hasler BP, Martin CS, Wood DS, Rosario B, Clark DB. A longitudinal study of insomnia and other sleep complaints in

        adolescents with and without alcohol use disorders. Alcoholism: Clinical and Experimental Research, 38, 2225-2233, 2014.

        PMCID: PMC4146702

     7.     Frank E, Sidor MM, Gamble KL, Cirelli C, Sharkey KM, Hoyle N, Tikotzky L, Talbot LS, McCarthy MJ, Hasler BP. Circadian

        clocks, brain function, and development. Annals of the NY Academy of Sciences. 1306, 43-67, 2013. PMID: 24329517

     8.     Hasler BP, Sitnick SL, Shaw DS, Forbes EE. An altered neural response to reward may contribute to alcohol problems among

        late adolescents with an evening chronotype. Psychiatry Research: Neuroimaging, 214, 357-364, 2013. PMCID: PMC3852171

     9.     Hasler BP, Insana SP, James JA, Germain A. Evening-type military veterans report worse lifetime posttraumatic stress

        symptoms and greater brainstem activity across wakefulness and REM sleep. Biological Psychology, 94, 255-252, 2013.

        PMCID: PMC3797161

     10.     Roecklein KA, Carney CE, Wong PM, Steiner JL, Hasler BP, Franzen PL. The role of beliefs and attitudes about sleep in

        seasonal and nonseasonal mood disorder, and nondepressed controls. Journal of Affective Disorders, 150, 466-473, 2013.

        PMCID: PMC3968775

     11.     Hasler BP, Clark DB. Circadian misalignment, reward functioning, and adolescent alcohol involvement. Alcoholism: Clinical

        and Experimental Research. 37(4), 558-565, 2013. PMCID: PMC3843484

     12.     Clark DB, Chung T, Pajtek S, Zhai Z, Long E, Hasler B.  Neuroimaging methods for adolescent substance use disorder

        prevention science.  Prevention Science. 14(3), 300-309, 2013. PMCID: PMC3640678

     13.     Hasler BP, Dahl RE, Holm SM, Jakubcak JL, Ryan ND, Silk JS, Phillips ML, Forbes EE. Weekend-weekday advances in sleep

        timing are associated with altered reward-related brain function in healthy adolescents. Biological Psychology, 91, 334-341,

        2012. PMCID: PMC3490026

     14.     Velo J, Stewart JL, Hasler BP, Towers DN, Allen JJB. Should it matter when we record? Time of year and time of day as factors

        influencing frontal EEG asymmetry. Biological Psychology, 91, 283-291, 2012. PMCID: PMC3530616

     15.     Roecklein KA, Wong PM, Franzen PL, Hasler BP, Wood-Vasey WM, Nimgaonkar VL, Miller MA, Ferrell RE, Manuck SB.

        Melanopsin gene variations interact with season to predict sleep timing and chronotype. Chronobiology International, 29,

        1036-1047, 2012. PMCID: PMC3724237

     16.     Hasler BP, Germain A, Nofzinger EA, Kupfer DJ, Krafty RT, Rothenberger SD, James JA, Bi W, Buysse DJ.  Chronotype and

        diurnal patterns of positive affect and affective neural circuitry in primary insomnia.  Journal of Sleep Research, 21, 515-526,

        2012. PMCID: PMC3371278

     17.     Soreca I, Lotz M, Frank E, Hasler BP, Levenson J, Kupfer DJ. Sleep duration is associated with dyslipidemia in patients with

        bipolar disorder in clinical remission. Journal of Affective Disorders, 141, 484-487, 2012. PMCID: PMC3612347

     18.     Hasler BP, Smith LJ, Cousins JC, Bootzin RR.  Circadian rhythms, sleep, and substance abuse.  Sleep Medicine Reviews,

       16(1), 67-81, 2012. PMCID: PMC3177010

     19.     Hasler BP, Troxel WM.  Couples’ nighttime sleep efficiency and concordance: Evidence for bidirectional associations with

        daytime relationship functioning. Psychosomatic Medicine, 72(8), 794-801, 2010. PMCID: PMC2950886

     20.     Hasler BP, Buysse DJ, Kupfer DJ, Germain A.  Phase relationships between core body temperature, melatonin, and sleep are

        associated with depression severity: Further evidence for circadian misalignment in non-seasonal depression. Psychiatry

        Research, 178(1), 205-207, 2010. PMCID: PMC2914120

     21.     Britton WB, Bootzin, RR, Cousins JC, Hasler BP, Peck T, Shapiro SL. The contribution of mindfulness practice to a

        multi-component behavioral sleep intervention following substance abuse treatment in adolescents: A treatment development

        study. Substance Abuse, 31(2), 86-97, 2010.

     22.     Hasler BP, Allen JJB, Sbarra DA, Bootzin RR, Bernert RA. Morningness-eveningness and depression: Preliminary evidence for

        the role of BAS and positive affect. Psychiatry Research, 176, 166-173, 2010. PMCID: PMC2844473

     23.     Rohrbaugh MJ, Shoham V, Butler EA, Hasler BP, Berman JS. Affective synchrony in dual- and single-smoker couples: Further

        evidence of "symptom-system fit"? Family Process, 48(1), 55-67, 2009. PMCID: PMC2774814

     24.     Hasler BP, Mehl MR, Bootzin RR, Vazire S. Preliminary evidence of diurnal rhythms in everyday behaviors associated with

        positive affect. Journal of Research in Personality, 42(6), 1537-1546, 2008.

     25.     Hasler BP, Bootzin RR, Cousins JC, Fridel K, Wenk GL. Circadian phase in sleep-disturbed adolescents with a history of

        substance abuse. Behavioral Sleep Medicine, 6(1), 55-73, 2008.

     26.     Lewy AJ, Emens JS, Sack RL, Hasler B, Bernert RA. Zeitgeber hierarchy in humans: resetting the circadian phase positions of

        blind people using melatonin. Chronobiology International, 20(5), 837-852, 2003.

     27.     Lewy AJ, Emens JS, Sack RL, Hasler BP, Bernert RA. Low, but not high, doses of melatonin entrained a free-running blind

        person with a long circadian period. Chronobiology International, 19(3), 649-658, 2002.

     28.     Lewy AJ, Hasler BP, Emens JS, Sack RL. Pretreatment circadian period in free-running blind people may predict the phase

        angle of entrainment to melatonin. Neuroscience Letters, 313(3), 158-160, 2001.

     29.     Lewy AJ, Bauer VK, Hasler BP, Kendall AR, Pires MLN, Sack RL. Capturing the circadian rhythms of free-running blind people

        with 0.5 mg melatonin. Brain Research, 918(1-2), 96-100, 2001.