2021 Publications

Abdalla M, Sakhuja S, Akinyelure OP, Thomas SJ, Schwartz JE, Lewis CE, Shikany JM, Lloyd-Jones D, Booth JN, 3rd, Shimbo D, Hall MH, & Muntner P. The association of actigraphy-assessed sleep duration with sleep blood pressure, nocturnal hypertension, and nondipping blood pressure: the coronary artery risk development in young adults (CARDIA) study. J Hypertens 2021; 39(12), 2478-2487. doi:10.1097/hjh.0000000000002956 PMID: 34738991 ‘PMC8571489: ‘PMC8571489^

Aguinaldo LD, Goldstone A, Hasler BP, Brent DA, Coronado C, & Jacobus J. Preliminary analysis of low-level alcohol use and suicidality with children in the adolescent brain and cognitive development (ABCD) baseline cohort. Psychiatry Res 2021; 299, 113825. doi:10.1016/j.psychres.2021.113825 PMID: 33713937 ‘PMC8224175: ‘PMC8224175^

Allen HL, Gmelin T, Moored KD, Boudreau RM, Smagula SF, Cohen RW, Katz R, Stone K, Cauley JA, & Glynn NW. Relationship Between Personality Measures and Perceived Mental Fatigability. J Aging Health 2021, 8982643211055032. doi:10.1177/08982643211055032 PMID: 34821521 ‘PMC9130341: ‘PMC9130341^

Alsameen M, DiFrancesco MW, Drummond SPA, Franzen PL, & Beebe DW. Neuronal activation and performance changes in working memory induced by chronic sleep restriction in adolescents. J Sleep Res 2021; 30(5), e13304. doi:10.1111/jsr.13304 PMID: 33615598 ‘PMC8462989: ‘PMC8462989^

Banihashemi L, Peng CW, Verstynen T, Wallace ML, Lamont DN, Alkhars HM, Yeh FC, Beeney JE, Aizenstein HJ, & Germain A. Opposing relationships of childhood threat and deprivation with stria terminalis white matter. Hum Brain Mapp 2021; 42(8), 2445-2460. doi:10.1002/hbm.25378 PMID: 33739544 ‘PMC8090789: ‘PMC8090789^

Barham WT, Buysse DJ, Kline CE, Kubala AG, & Brindle RC. Sleep health mediates the relationship between physical activity and depression symptoms. Sleep Breath 2021, 1-9. doi:10.1007/s11325-021-02496-9 PMID: 34561758 ‘PMC8475358: ‘PMC8475358^

Baron KG, Duffecy J, Reutrakul S, Levenson JC, McFarland MM, Lee S, & Qeadan F. Behavioral interventions to extend sleep duration: A systematic review and meta-analysis. Sleep Med Rev 2021; 60, 101532. doi:10.1016/j.smrv.2021.101532 PMID: 34507028

Birmaher B, Merranko J, Hafeman D, Goldstein BI, Diler R, Levenson JC, Monk K, Iyengar S, Hickey MB, Sakolsky D, Axelson D, & Goldstein T. A Longitudinal Study of Psychiatric Disorders in Offspring of Parents With Bipolar Disorder From Preschool to Adolescence. J Am Acad Child Adolesc Psychiatry 2021; 60(11), 1419-1429. doi:10.1016/j.jaac.2021.02.023 PMID: 33785405 ‘PMC8473582: ‘PMC8473582^

Bowman MA, Kline CE, Buysse DJ, Kravitz HM, Joffe H, Matthews KA, Bromberger JT, Roecklein KA, Krafty RT, & Hall MH. Longitudinal Association Between Depressive Symptoms and Multidimensional Sleep Health: The SWAN Sleep Study. Ann Behav Med 2021; 55(7), 641-652. doi:10.1093/abm/kaaa107 PMID: 33410460 ‘PMC8240133: ‘PMC8240133^

Brown MM, Arigo D, Wolever RQ, Smoski MJ, Hall MH, Brantley JG, & Greeson JM. Do gender, anxiety, or sleep quality predict mindfulness-based stress reduction outcomes? J Health Psychol 2021; 26(13), 2656-2662. doi:10.1177/1359105320931186 PMID: 32489109 ‘PMC7814316: ‘PMC7814316^

Chung J, Goodman M, Huang T, Wallace ML, Johnson DA, Bertisch S, & Redline S. Racial-ethnic Differences in Actigraphy, Questionnaire, and Polysomnography Indicators of Healthy Sleep: The Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol 2021. doi:10.1093/aje/kwab232 PMID: 34498675

Coelho J, Lopez R, Richaud A, Buysse DJ, Wallace ML, Philip P, & Micoulaud-Franchi JA. Toward a multi-lingual diagnostic tool for the worldwide problem of sleep health: The French RU-SATED validation. J Psychiatr Res 2021; 143, 341-349. doi:10.1016/j.jpsychires.2021.09.008 PMID: 34563876

Conlon RPK, Wang B, Germeroth LJ, Cheng Y, Buysse DJ, & Levine MD. Demographic, Pregnancy-Related, and Health-Related Factors in Association with Changes in Sleep Among Pregnant Women with Overweight or Obesity. Int J Behav Med 2021; 28(2), 200-206. doi:10.1007/s12529-020-09887-4 PMID: 32378048

Delisle BP, George AL, Jr., Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer F, Shivkumar K, Shea SA, & Balijepalli RC. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects. Circ Arrhythm Electrophysiol 2021; 14(11), e010181. doi:10.1161/circep.121.010181 PMID: 34719240 ‘PMC8815462: ‘PMC8815462^

Delisle BP, George AL, Jr., Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer F, Shivkumar K, Shea SA, & Balijepalli RC. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations. Circ Arrhythm Electrophysiol 2021; 14(11), e010190. doi:10.1161/circep.121.010190 PMID: 34719257 ‘PMC8865094: ‘PMC8865094^

Dubowitz T, Haas A, Ghosh-Dastidar B, Collins RL, Beckman R, Brooks Holliday S, Richardson AS, Hale L, Buysse DJ, Buman MP, & Troxel WM. Does investing in low-income urban neighborhoods improve sleep? Sleep 2021; 44(6). doi:10.1093/sleep/zsaa292 PMID: 33417708 ‘PMC8193558: ‘PMC8193558^

Duffy JF, Abbott SM, Burgess HJ, Crowley SJ, Emens JS, Epstein LJ, Gamble KL, Hasler BP, Kristo DA, Malkani RG, Rahman SA, Thomas SJ, Wyatt JK, Zee PC, & Klerman EB. Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities. Sleep 2021; 44(5). doi:10.1093/sleep/zsaa281 PMID: 33582815 ‘PMC8120340: ‘PMC8120340^

Evans MA, Buysse DJ, Marsland AL, Wright AGC, Foust J, Carroll LW, Kohli N, Mehra R, Jasper A, Srinivasan S, & Hall MH. Meta-analysis of age and actigraphy-assessed sleep characteristics across the lifespan. Sleep 2021; 44(9). doi:10.1093/sleep/zsab088 PMID: 33823052 ‘PMC8436145: ‘PMC8436145^

Gaffey AE, Schwartz JE, Harris KM, Hall MH, & Burg MM. Effects of ambulatory blood pressure monitoring on sleep in healthy, normotensive men and women. Blood Press Monit 2021; 26(2), 93-101. doi:10.1097/mbp.0000000000000494 PMID: 33136653 ‘PMC7933045: ‘PMC7933045^

Germain A, Markwald RR, King E, Bramoweth AD, Wolfson M, Seda G, Han T, Miggantz E, O’Reilly B, Hungerford L, Sitzer T, Mysliwiec V, Hout JJ, & Wallace ML. Enhancing behavioral sleep care with digital technology: study protocol for a hybrid type 3 implementation-effectiveness randomized trial. Trials 2021; 22(1), 46. doi:10.1186/s13063-020-04974-z PMID: 33430955 ‘PMC7798254: ‘PMC7798254^

Harvey AG, Dong L, Hein K, Yu SH, Martinez AJ, Gumport NB, Smith FL, Chapman A, Lisman M, Mirzadegan IA, Mullin AC, Fine E, Dolsen MR, Gasperetti CE, Bukosky J, Alvarado-Martinez CG, Kilbourne AM, Rabe-Hesketh S, & Buysse DJ. A randomized controlled trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) to improve serious mental illness outcomes in a community setting. J Consult Clin Psychol 2021; 89(6), 537-550. doi:10.1037/ccp0000650 PMID: 34264701

Hasler BP, & McClung CA. Delayed circadian rhythms and substance abuse: dopamine transmission’s time has come. J Clin Invest 2021; 131(18). doi:10.1172/jci152832 PMID: 34523611 ‘PMC8439586 exists.: ‘PMC8439586 exists.^

Hasler BP, Soehner AM, Wallace ML, Logan RW, Ngari W, Forbes EE, Buysse DJ, & Clark DB. Experimentally imposed circadian misalignment alters the neural response to monetary rewards and response inhibition in healthy adolescents. Psychol Med 2021, 1-9. doi:10.1017/s0033291721000787 PMID: 33729109 ‘PMC8935965: ‘PMC8935965^

Hawkins MS, Levine MD, Buysse DJ, Abebe KZ, Hsiao WH, McTigue KM, & Davis EM. Sleep Health Characteristics among Adults Who Attempted Weight Loss in the Past Year: NHANES 2017-2018. Int J Environ Res Public Health 2021; 18(19). doi:10.3390/ijerph181910170 PMID: 34639473 ‘PMC8507873: ‘PMC8507873^

Hisler GC, Rothenberger SD, Clark DB, & Hasler BP. Is there a 24-hour rhythm in alcohol craving and does it vary by sleep/circadian timing? Chronobiol Int 2021; 38(1), 109-121. doi:10.1080/07420528.2020.1838532 PMID: 33167734 ‘PMC7855555: ‘PMC7855555^

Holliday SB, Haas A, Dong L, Ghosh-Dastidar M, Hale L, Buysse DJ, Dubowitz T, & Troxel WM. Examining the diagnostic validity of the Berlin Questionnaire in a low-income Black American sample. J Clin Sleep Med 2021; 17(10), 1987-1994. doi:10.5664/jcsm.9388 PMID: 33969821 ‘PMC8494099: ‘PMC8494099^

Jalbrzikowski M, Hayes RA, Scully KE, Franzen PL, Hasler BP, Siegle GJ, Buysse DJ, Dahl RE, Forbes EE, Ladouceur CD, McMakin DL, Ryan ND, Silk JS, Goldstein TR, & Soehner AM. Associations between brain structure and sleep patterns across adolescent development. Sleep 2021; 44(10). doi:10.1093/sleep/zsab120 PMID: 33971013 ‘PMC8503824: ‘PMC8503824^

Kaufman EA, Graves JL, Wallace ML, Lazarus SA, Stepp SD, & Pedersen SL. Associations between physiological and self-reported indices of emotion dysregulation across varying levels of alcohol use among individuals with and without borderline personality disorder. Biol Psychol 2021; 160, 108044. doi:10.1016/j.biopsycho.2021.108044 PMID: 33571567

Kline CE, Chasens ER, Bizhanova Z, Sereika SM, Buysse DJ, Imes CC, Kariuki JK, Mendez DD, Cajita MI, Rathbun SL, & Burke LE. The association between sleep health and weight change during a 12-month behavioral weight loss intervention. Int J Obes (Lond) 2021; 45(3), 639-649. doi:10.1038/s41366-020-00728-8 PMID: 33414489 ‘PMC7914147: ‘PMC7914147^

Kline CE, Colvin AB, Pettee Gabriel K, Karvonen-Gutierrez CA, Cauley JA, Hall MH, Matthews KA, Ruppert KM, Neal-Perry GS, Strotmeyer ES, & Sternfeld B. Associations between longitudinal trajectories of insomnia symptoms and sleep duration with objective physical function in postmenopausal women: the Study of Women’s Health Across the Nation. Sleep 2021; 44(8). doi:10.1093/sleep/zsab059 PMID: 33705558 ‘PMC8361301: ‘PMC8361301^

Levenson JC, Ford HA, Reyes ZMD, Mukundan A, Patel G, Bahary S, & Miller E. Designing adolescent sleep interventions with stakeholder input. Sleep Health 2021; 7(5), 581-587. doi:10.1016/j.sleh.2021.07.007 PMID: 34474988 ‘PMC8545848: ‘PMC8545848^

Levenson JC, Thoma BC, Hamilton JL, Choukas-Bradley S, & Salk RH. Sleep among gender minority adolescents. Sleep 2021; 44(3). doi:10.1093/sleep/zsaa185 PMID: 32949142 ‘PMC7953209: ‘PMC7953209^

Madrid-Valero JJ, Barclay NL, Rowe R, Perach R, Buysse DJ, Ordoñana JR, Eley TC, & Gregory AM. Association between symptoms of sleep apnea and problem behaviors in young adult twins and siblings. Psychol Med 2021; 51(7), 1175-1182. doi:10.1017/s0033291719004070 PMID: 32026794

Matthews KA, Lee L, Kravitz HM, Joffe H, Neal-Perry G, Swanson LM, Evans MA, & Hall MH. Influence of the menopausal transition on polysomnographic sleep characteristics: a longitudinal analysis. Sleep 2021; 44(11). doi:10.1093/sleep/zsab139 PMID: 34081126 ‘PMC8598193: ‘PMC8598193^

McLean SA, Ressler K, Koenen KC, Neylan T, Germine L, Jovanovic T, Clifford GD, Zeng D, An X, Linnstaedt S, Beaudoin F, House S, Bollen KA, Musey P, Hendry P, Jones CW, Lewandowski C, Swor R, Datner E, Mohiuddin K, Stevens JS, Storrow A, Kurz MC, McGrath ME, Fermann GJ, Hudak LA, Gentile N, Chang AM, Peak DA, Pascual JL, Seamon MJ, Sergot P, Peacock WF, Diercks D, Sanchez LD, Rathlev N, Domeier R, Haran JP, Pearson C, Murty VP, Insel TR, Dagum P, Onnela JP, Bruce SE, Gaynes BN, Joormann J, Miller MW, Pietrzak RH, Buysse DJ, Pizzagalli DA, Rauch SL, Harte SE, Young LJ, Barch DM, Lebois LAM, van Rooij SJH, Luna B, Smoller JW, Dougherty RF, Pace TWW, Binder E, Sheridan JF, Elliott JM, Basu A, Fromer M, Parlikar T, Zaslavsky AM, & Kessler R. Correction: The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure. Mol Psychiatry 2021; 26(7), 3658. doi:10.1038/s41380-020-00897-y PMID: 32989243

Morris JL, Mazzotti DR, Gottlieb DJ, & Hall MH. Sex differences within symptom subtypes of mild obstructive sleep apnea. Sleep Med 2021; 84, 253-258. doi:10.1016/j.sleep.2021.06.001 PMID: 34182353 ‘PMC8364755: ‘PMC8364755^

Nielson SA, Buysse DJ, & Kay DB. Fidelity of Information Processing on a Psychomotor Vigilance Task Predicts Changes in Self-Reported Sleepiness Ratings. Nat Sci Sleep 2021; 13, 659-671. doi:10.2147/nss.S301832 PMID: 34079410 ‘PMC8164875: ‘PMC8164875^

Omowale SS, Casas A, Lai YH, Sanders SA, Hill AV, Wallace ML, Rathbun SL, Gary-Webb TL, Burke LE, Davis EM, & Mendez DD. Trends in Stress Throughout Pregnancy and Postpartum Period During the COVID-19 Pandemic: Longitudinal Study Using Ecological Momentary Assessment and Data From the Postpartum Mothers Mobile Study. JMIR Ment Health 2021; 8(9), e30422. doi:10.2196/30422 PMID: 34328420 ‘PMC8457341: ‘PMC8457341^

Patterson PD, Liszka MK, McIlvaine QS, Nong L, Weaver MD, Turner RL, Platt TE, Opitz SE, Guyette FX, Martin-Gill C, Weiss LS, Buysse DJ, & Callaway CW. Does the evidence support brief (≤30-mins), moderate (31-60-mins), or long duration naps (61+ mins) on the night shift? A systematic review. Sleep Med Rev 2021; 59, 101509. doi:10.1016/j.smrv.2021.101509 PMID: 34116386

Patterson PD, Martin-Gill C, & Buysse DJ. Commentary on Dawson et al.: Fatigue risk management in emergency services personnel. Sleep Med Rev 2021; 57, 101484. doi:10.1016/j.smrv.2021.101484 PMID: 33865012

Patterson PD, Mountz KA, Agostinelli MG, Weaver MD, Yu YC, Herbert BM, Markosyan MA, Hopkins DR, Alameida AC, Maloney Iii JA, Martin SE, Brassil BN, Martin-Gill C, Guyette FX, Callaway CW, & Buysse DJ. Ambulatory blood pressure monitoring among emergency medical services night shift workers. Occup Environ Med 2021; 78(1), 29-35. doi:10.1136/oemed-2020-106459 PMID: 32847989

Price RB, Gillan CM, Hanlon C, Ferrarelli F, Kim T, Karim HT, Renard M, Kaskie R, Degutis M, Wears A, Vienneau EP, Peterchev AV, Brown V, Siegle GJ, Wallace ML, & Ahmari SE. Effect of Experimental Manipulation of the Orbitofrontal Cortex on Short-Term Markers of Compulsive Behavior: A Theta Burst Stimulation Study. Am J Psychiatry 2021; 178(5), 459-468. doi:10.1176/appi.ajp.2020.20060821 PMID: 33726523 ‘PMC8119344: ‘PMC8119344^

Ratcliff CG, Zepeda SG, Hall MH, Tullos EA, Fowler S, Chaoul A, Spelman A, Arun B, & Cohen L. Patient characteristics associated with sleep disturbance in breast cancer survivors. Support Care Cancer 2021; 29(5), 2601-2611. doi:10.1007/s00520-020-05777-3 PMID: 32964261 ‘PMC7981239: ‘PMC7981239^

Richardson AS, Troxel WM, Ghosh-Dastidar M, Hunter GP, Beckman R, Collins R, Brooks Holliday S, Nugroho A, Hale L, Buysse DJ, Buman MP, & Dubowitz T. Violent crime, police presence and poor sleep in two low-income urban predominantly Black American neighbourhoods. J Epidemiol Community Health 2021; 75(1), 62-68. doi:10.1136/jech-2020-214500 PMID: 32847962 ‘PMC8152929: ‘PMC8152929^

Roecklein KA, Franzen PL, Wescott DL, Hasler BP, Miller MA, Donofry SD, DuPont CM, Gratzmiller SM, Drexler SP, Wood-Vasey WM, & Gamlin PD. Melanopsin-driven pupil response in summer and winter in unipolar seasonal affective disorder. J Affect Disord 2021; 291, 93-101. doi:10.1016/j.jad.2021.04.084 PMID: 34029883 ‘PMC8693789: ‘PMC8693789^

Sancho-Domingo C, Carballo JL, Coloma-Carmona A, & Buysse DJ. Brief version of the Pittsburgh Sleep Quality Index (B-PSQI) and measurement invariance across gender and age in a population-based sample. Psychol Assess 2021; 33(2), 111-121. doi:10.1037/pas0000959 PMID: 33119375

Smagula SF. Potential Implications of Evidence for Apathy’s Brain Structural Basis. Am J Geriatr Psychiatry 2021; 29(4), 333-335. doi:10.1016/j.jagp.2021.01.012 PMID: 33518463

Smagula SF, Capps CS, & Krafty RT. Evaluating the timing of differences in activity related to depression symptoms across adulthood in the United States. J Affect Disord 2021; 284, 64-68. doi:10.1016/j.jad.2021.01.069 PMID: 33582433 ‘PMC7958982: ‘PMC7958982^

Smagula SF, Karim HT, Ibrahim TS, Krafty RT, Stahl ST, Rodakowski J, Reynolds CF, Hall MH, & Aizenstein HJ. Resting-State Function Connectivity Associated With Being a “Morning-Type” Dementia Caregiver and Having Lower Depression Symptom Severity. J Gerontol B Psychol Sci Soc Sci 2021; 76(6), 1071-1076. doi:10.1093/geronb/gbaa115 PMID: 32750139 ‘PMC8200349: ‘PMC8200349^

Smagula SF, Sofer T, Guo N, Prerau M, Purcell S, Mariani S, Yaffe K, Redline S, & Stone KL. Spectral sleep electroencephalographic correlates of sleep efficiency, and discrepancies between actigraphy and self-reported measures, in older men. J Sleep Res 2021; 30(2), e13033. doi:10.1111/jsr.13033 PMID: 32198950 ‘PMC7607534: ‘PMC7607534^

Stahl ST, Neagoe I, Smagula SF, Posluszny D, & Bovbjerg DH. Cancer Bereavement and Depression Symptoms in Older Spouses: The Possible Modifying Role of the Circadian Rest-Activity Rhythm. Clin Gerontol 2021; 44(2), 126-132. doi:10.1080/07317115.2020.1812787 PMID: 32856562 ‘PMC7886956: ‘PMC7886956^

Stahl ST, Rodakowski J, & Smagula SF. Timing of Daily Activities over a 24-Hour Period and Affective Status among a National Cohort of Older Dementia Caregivers. J Aging Health 2021; 33(1-2), 125-132. doi:10.1177/0898264320962363 PMID: 32975475 ‘PMC7856063: ‘PMC7856063^

Stahl ST, Smagula SF, Rodakowski J, Dew MA, Karp JF, Albert SM, Butters M, Gildengers A, & Reynolds CF, 3rd. Subjective Sleep Quality and Trajectories of Interleukin-6 in Older Adults. Am J Geriatr Psychiatry 2021; 29(2), 204-208. doi:10.1016/j.jagp.2020.06.019 PMID: 32680764 ‘PMC7759575: ‘PMC7759575^

Swanson LM, Hood MM, Hall MH, Kravitz HM, Matthews KA, Joffe H, Thurston RC, Butters MA, Ruppert K, & Harlow SD. Associations between sleep and cognitive performance in a racially/ethnically diverse cohort: the Study of Women’s Health Across the Nation. Sleep 2021; 44(2). doi:10.1093/sleep/zsaa182 PMID: 32918472 ‘PMC7879413: ‘PMC7879413^

Szigethy E, Tansel A, Pavlick AN, Marroquin MA, Serio CD, Silfee V, Wallace ML, Kingsley MJ, & Levinthal DJ. A Coached Digital Cognitive Behavioral Intervention Reduces Anxiety and Depression in Adults With Functional Gastrointestinal Disorders. Clin Transl Gastroenterol 2021; 12(12), e00436. doi:10.14309/ctg.0000000000000436 PMID: 34874018 ‘PMC8751763 contributions: E.S.: planned the study, conducted statistical analyses, interpreted data, and drafted the manuscript. A.T. planned the study, conducted statistical analyses, interpreted data, and drafted the manuscript. A.N.P. conducted the study and drafted the manuscript. M.A.M. conducted the study. C.D.S. planned the study and drafted the manuscript. V.S. planned the study and drafted the manuscript. M.L.W. conducted statistical analysis. M.J.K. planned the study and drafted the manuscript. D.J.L. planned the study, interpreted data, and drafted the manuscript. Financial support: No external grant funds were used in this study. RxWell is owned by the University of Pittsburgh Medical Center and is managed by the UPMC Health Plan’s Behavioral Unit of Digitally Delivered Interventions (BUDDI). The digital coaches were employed by the Department of Psychiatry and paid for by UPMC. Potential competing interests: D.J.L. is a consultant for Takeda Pharmaceuticals and Alexza Pharmaceuticals. None of the other authors have any conflicts of interest to declare.: ‘PMC8751763 contributions: E.S.: planned the study, conducted statistical analyses, interpreted data, and drafted the manuscript. A.T. planned the study, conducted statistical analyses, interpreted data, and drafted the manuscript. A.N.P. conducted the study and drafted the manuscript. M.A.M. conducted the study. C.D.S. planned the study and drafted the manuscript. V.S. planned the study and drafted the manuscript. M.L.W. conducted statistical analysis. M.J.K. planned the study and drafted the manuscript. D.J.L. planned the study, interpreted data, and drafted the manuscript. Financial support: No external grant funds were used in this study. RxWell is owned by the University of Pittsburgh Medical Center and is managed by the UPMC Health Plan’s Behavioral Unit of Digitally Delivered Interventions (BUDDI). The digital coaches were employed by the Department of Psychiatry and paid for by UPMC. Potential competing interests: D.J.L. is a consultant for Takeda Pharmaceuticals and Alexza Pharmaceuticals. None of the other authors have any conflicts of interest to declare.^

Tighe CA, Brindle RC, Stahl ST, Wallace ML, Bramoweth AD, Forman DE, & Buysse DJ. Multidimensional Sleep Health and Physical Functioning in Older Adults. Gerontol Geriatr Med 2021; 7, 23337214211016222. doi:10.1177/23337214211016222 PMID: 34095350 ‘PMC8142238: ‘PMC8142238^

Tracy EL, Chin B, Lehrer HM, Carroll LW, Buysse DJ, & Hall MH. Coping strategies moderate the effect of perceived stress on sleep and health in older adults during the COVID-19 pandemic. Stress Health 2021. doi:10.1002/smi.3124 PMID: 34951930

Tuft M, Hall MH, & Krafty RT. Spectra in low-rank localized layers (SpeLLL) for interpretable time-frequency analysis. Biometrics 2021. doi:10.1111/biom.13577 PMID: 34609738 ‘PMC8980115: ‘PMC8980115^

Vaughn-Coaxum RA, Merranko J, Birmaher B, Dickstein DP, Hafeman D, Levenson JC, Liao F, Gill MK, Hower H, Goldstein BI, Strober M, Ryan ND, Diler R, Keller MB, Yen S, Weinstock LM, Axelson D, & Goldstein TR. Longitudinal course of depressive symptom severity among youths with bipolar disorders: Moderating influences of sustained attention and history of child maltreatment. J Affect Disord 2021; 282, 261-271. doi:10.1016/j.jad.2020.12.078 PMID: 33418377 ‘PMC8073228: ‘PMC8073228^

Wallace ML, Coleman TS, Mentch LK, Buysse DJ, Graves JL, Hagen EW, Hall MH, Stone KL, Redline S, & Peppard PE. Physiological sleep measures predict time to 15-year mortality in community adults: Application of a novel machine learning framework. J Sleep Res 2021; 30(6), e13386. doi:10.1111/jsr.13386 PMID: 33991144 ‘PMC8591145: ‘PMC8591145^

Wallace ML, Yu L, Buysse DJ, Stone KL, Redline S, Smagula SF, Stefanick ML, Kritz-Silverstein D, & Hall MH. Multidimensional sleep health domains in older men and women: an actigraphy factor analysis. Sleep 2021; 44(2). doi:10.1093/sleep/zsaa181 PMID: 32918075 ‘PMC7879411: ‘PMC7879411^

Wilckens KA, Stillman CM, Waiwood AM, Kang C, Leckie RL, Peven JC, Foust JE, Fraundorf SH, & Erickson KI. Exercise interventions preserve hippocampal volume: A meta-analysis. Hippocampus 2021; 31(3), 335-347. doi:10.1002/hipo.23292 PMID: 33315276

Wong PM, Hasler BP, Kamarck TW, Wright AGC, Hall M, Carskadon MA, Gao L, & Manuck SB. Day-to-day associations between sleep characteristics and affect in community dwelling adults. J Sleep Res 2021; 30(5), e13297. doi:10.1111/jsr.13297 PMID: 33588521 ‘PMC8637582: ‘PMC8637582^

Zilcha-Mano S, Wallace ML, Brown PJ, Sneed J, Roose SP, & Rutherford BR. Who benefits most from expectancy effects? A combined neuroimaging and antidepressant trial in depressed older adults. Transl Psychiatry 2021; 11(1), 475. doi:10.1038/s41398-021-01606-1 PMID: 34526482 ‘PMC8443672 takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs. Zilcha-Mano, Brown, Sneed, Rutherford, and Roose have no disclosures or conflicts of interest to report. Dr. Wallace receives statistical consulting fees from Noctem and grant funding from the National Institute on Aging, both unrelated to this work. This paper has not been previously presented.: ‘PMC8443672 takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs. Zilcha-Mano, Brown, Sneed, Rutherford, and Roose have no disclosures or conflicts of interest to report. Dr. Wallace receives statistical consulting fees from Noctem and grant funding from the National Institute on Aging, both unrelated to this work. This paper has not been previously presented.^

Hashash JG, Knisely MR, Germain A, McAuliff K, Strassburger M, Vachon A, Binion DG, Regueiro M, Wallace M, & Szigethy E. Brief Behavioral Therapy and Bupropion for Sleep and Fatigue in Young Adults With Crohn’s Disease: An Exploratory Open Trial Study. Clin Gastroenterol Hepatol 2022; 20(1), 96-104. doi:10.1016/j.cgh.2020.09.047 PMID: 33010410

Lehrer HM, Chu LE, Hall MH, & Murdock KW. Self-reported sleep efficiency and duration are associated with bioenergetic function in peripheral blood mononuclear cells (PBMCs) of adults. Mitochondrion 2022; 62, 122-127. doi:10.1016/j.mito.2021.11.005 PMID: 34785262 ‘PMC8724413: ‘PMC8724413^

Madrid-Valero JJ, Bowling N, Vafeiadou A, Buysse DJ, Banissy MJ, & Gregory AM. Sleep in adults from the UK during the first few months of the coronavirus outbreak. J Sleep Res 2022; 31(2), e13465. doi:10.1111/jsr.13465 PMID: 34453464

Smagula SF, Isenberg AS, Stahl ST, Alexopoulos GS, Reynolds CF, 3rd, & Rodakowski J. Adaptation and Pilot Study of a Behavioral Intervention Targeting Morning Activation Deficits in Dementia Caregivers: Scheduling Activity and Monitoring Mornings (SAMM). Am J Geriatr Psychiatry 2022; 30(4), 494-503. doi:10.1016/j.jagp.2021.09.017 PMID: 34753633

Carroll, JE, Teti, DM, Hall, MH, Christian, LM. Maternal Sleep in Pregnancy and Postpartum Part II: Biomechanisms and Intervention Strategies. Current psychiatry reports, 21:19, 2019. PMID: 30826895.

Christian, LM, Carroll, JE, Porter, K, Hall, MH. Sleep quality across pregnancy and postpartum: effects of parity and race. Sleep health, 2019. PMID: 31122875.

Christian, LM, Carroll, JE, Teti, DM, Hall, MH. Maternal Sleep in Pregnancy and Postpartum Part I: Mental, Physical, and Interpersonal Consequences. Current psychiatry reports, 21:20, 2019. PMID: 30826881.

Dalmases, M, Benitez, I, Sapina-Beltran, E, Garcia-Codina, O, Medina-Bustos, A, Escarrabill, J, Salto, E, Buysse, DJ, Plana, RE, Sanchez-de-la-Torre, M, Barbe, F, de Batlle, J. Impact of sleep health on self-perceived health status. Scientific reports, 9:7284, 2019. PMID: 31086269, PMC6513841.

DeSantis, AS, Dubowitz, T, Ghosh-Dastidar, B, Hunter, GP, Buman, M, Buysse, DJ, Hale, L, Troxel, WM. A preliminary study of a composite sleep health score: associations with psychological distress, body mass index, and physical functioning in a low-income African American community. Sleep health, 2019. PMID: 31208939.

Dong, L, Martinez, AJ, Buysse, DJ, Harvey, AG. A composite measure of sleep health predicts concurrent mental and physical health outcomes in adolescents prone to eveningness. Sleep health, 5:166-174, 2019. PMID: 30928117, PMC6452900.

Germeroth, LJ, Wallace, ML, Levine, MD. Taste manipulation during a food cue-reactivity task: Effects on cue-elicited food craving and subsequent food intake among individuals with overweight and obesity. Eating behaviors, 33:61-66, 2019. PMID: 30959242, PMC6535365.

Goldstone, A, Willoughby, AR, de Zambotti, M, Clark, DB, Sullivan, EV, Hasler, BP, Franzen, PL, Prouty, DE, Colrain, IM, Baker, FC. Sleep spindle characteristics in adolescents. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 130:893-902, 2019. PMID: 30981174.

Gunn, HE, Tutek, J, Buysse, DJ. Brief Behavioral Treatment of Insomnia. Sleep medicine clinics, 14:235-243, 2019. PMID: 31029189.

Hamilton, JL, Stange, JP, Burke, TA, Franzen, PL, Alloy, LB. Sleep disturbance and physiological regulation among young adults with prior depression. Journal of psychiatric research, 115:75-81, 2019. PMID: 31121395, PMC6582965.

Hasler, BP, Bruce, S, Scharf, D, Ngari, W, Clark, DB. Circadian misalignment and weekend alcohol use in late adolescent drinkers: preliminary evidence. Chronobiology international, 36:796-810, 2019. PMID: 30950299, PMC6499627.

Hasler, BP, Wallace, ML, White, SJ, Molina, BSG, Pedersen, SL. Preliminary Evidence That Real World Sleep Timing and Duration are Associated With Laboratory-Assessed Alcohol Response. Alcoholism, clinical and experimental research, 43:1575-1584, 2019. PMID: 31070238.

He, S, Hasler, BP, Chakravorty, S. Alcohol and sleep-related problems. Current opinion in psychology, 30:117-122, 2019. PMID: 31128400.

Kay, DB, Karim, HT, Hasler, BP, James, JA, Germain, A, Hall, MH, Franzen, PL, Price, JC, Nofzinger, EA, Buysse, DJ. Impact of acute sleep restriction on cerebral glucose metabolism during recovery non-rapid eye movement sleep among individuals with primary insomnia and good sleeper controls. Sleep medicine, 55:81-91, 2019. PMID: 30772698.

Lebensohn-Chialvo, F, Rohrbaugh, MJ, Hasler, BP. Fidelity Failures in Brief Strategic Family Therapy for Adolescent Drug Abuse: A Clinical Analysis. Family process, 58:305-317, 2019. PMID: 29709061, PMC6531342.

Makarem, N, Shechter, A, Carnethon, MR, Mullington, JM, Hall, MH, Abdalla, M. Sleep Duration and Blood Pressure: Recent Advances and Future Directions. Current hypertension reports, 21:33, 2019. PMID: 30953237.

Matthews, KA, Hall, MH, Lee, L, Kravitz, HM, Chang, Y, Appelhans, BM, Swanson, LM, Neal-Perry, GS, Joffe, H. Racial/ethnic disparities in women’s sleep duration, continuity, and quality, and their statistical mediators: Study of Women’s Health Across the Nation. Sleep, 42, 2019. PMID: 30778560, PMC6519910.

Mendez, DD, Sanders, SA, Karimi, HA, Gharani, P, Rathbun, SL, Gary-Webb, TL, Wallace, ML, Gianakas, JJ, Burke, LE, Davis, EM. Understanding Pregnancy and Postpartum Health Using Ecological Momentary Assessment and Mobile Technology: Protocol for the Postpartum Mothers Mobile Study. JMIR research protocols, 8:e13569, 2019. PMID: 31244478.

Oser, M, Wallace, ML, Solano, F, Szigethy, EM. Guided Digital Cognitive Behavioral Program for Anxiety in Primary Care: Propensity-Matched Controlled Trial. JMIR mental health, 6:e11981, 2019. PMID: 30946022, PMC6470461.

Patterson, PD, Ghen, JD, Antoon, SF, Martin-Gill, C, Guyette, FX, Weiss, PM, Turner, RL, Buysse, DJ. Does evidence support “banking/extending sleep” by shift workers to mitigate fatigue, and/or to improve health, safety, or performance? A systematic review. Sleep health, 2019. PMID: 31031179.

Patterson, PD, Moore, CG, Guyette, FX, Doman, JM, Weaver, MD, Sequeira, DJ, Werman, HA, Swanson, D, Hostler, D, Lynch, J, Russo, L, Hines, L, Swecker, K, Kroemer, AJ, Runyon, MS, Buysse, DJ. Real-Time Fatigue Mitigation with Air-Medical Personnel: The SleepTrackTXT2 Randomized Trial. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, 23:465-478, 2019. PMID: 30285519.

Patterson, PD, Weaver, MD, Markosyan, MA, Moore, CG, Guyette, FX, Doman, JM, Sequeira, DJ, Werman, HA, Swanson, D, Hostler, D, Lynch, J, Templin, MA, Rozario, NL, Russo, L, Hines, L, Swecker, K, Runyon, MS, Buysse, DJ. Impact of shift duration on alertness among air-medical emergency care clinician shift workers. American journal of industrial medicine, 62:325-336, 2019. PMID: 30734328.

Robbins, R, Grandner, MA, Buxton, OM, Hale, L, Buysse, DJ, Knutson, KL, Patel, SR, Troxel, WM, Youngstedt, SD, Czeisler, CA, Jean-Louis, G. Sleep myths: an expert-led study to identify false beliefs about sleep that impinge upon population sleep health practices. Sleep health, 2019. PMID: 31003950.

Schneider, MN, Denis, D, Buysse, DJ, Kovas, Y, Gregory, AM. Associations between pre-sleep arousal and insomnia symptoms in early adulthood: a twin and sibling study. Sleep, 42, 2019. PMID: 30722021.

Shi, X, Buysse, DJ, Ritterband, LM, Sereika, SM, Strollo, PJ, Wenzel, SE, Luyster, FS. Solving insomnia electronically: Sleep treatment for asthma (SIESTA): A study protocol for a randomized controlled trial. Contemporary clinical trials, 79:73-79, 2019. PMID: 30825525, PMC6563833.

Smagula, SF. New Evidence for a Biological Pathway to Mental Health Problems in Dementia Caregivers: Invited Commentary on the Article by Wells et al. (AMGP-1247). The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. PMID: 31285154.

Smagula, SF, Freedland, KE, Steinmeyer, BC, Wallace, MJ, Carney, RM, Carney, MW. Moderators of Response to Cognitive Behavior Therapy for Major Depression in Patients With Heart Failure. Psychosomatic medicine, 81:506-512, 2019. PMID: 31083052.

Smagula, SF, Hall, MH, Stahl, ST. Rest-activity rhythms and depression symptoms in older bereaved adults. International psychogeriatrics:1-2, 2019. PMID: 30761967.

Soehner, AM, Bertocci, MA, Levenson, JC, Goldstein, TR, Rooks, B, Merranko, J, Hafeman, D, Diler, R, Axelson, D, Goldstein, BI, Hickey, MB, Monk, K, Phillips, ML, Birmaher, B. Longitudinal Associations Between Sleep Patterns and Psychiatric Symptom Severity in High-Risk and Community Comparison Youth. Journal of the American Academy of Child and Adolescent Psychiatry, 58:608-617, 2019. PMID: 30851396.

Thurston, RC, Chang, Y, Buysse, DJ, Hall, MH, Matthews, KA. Hot flashes and Awakenings Among Midlife Women. Sleep, 2019. PMID: 31152182.

Troxel, WM, DeSantis, A, Richardson, AS, Beckman, R, Ghosh-Dastidar, B, Nugroho, A, Hale, L, Buysse, DJ, Buman, MP, Dubowitz, T. Neighborhood disadvantage is associated with actigraphy-assessed sleep continuity and short sleep duration. Sleep, 42, 2019. PMID: 30877767, PMC6424083.

Wallace, ML, Buysse, DJ, Redline, S, Stone, K, Ensrud, K, Leng, Y, Ancoli-Israel, S, Hall, MH. Multidimensional Sleep and Mortality in Older Adults: A Machine-Learning Comparison with Other Risk Factors. The journals of gerontology Series A, Biological sciences and medical sciences, 2019. PMID: 30778527.

Williams, ET, Buchanan, DT, Buysse, DJ, Thompson, HJ. Injury, Sleep, and Functional Outcome in Hospital Patients With Traumatic Brain Injury. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 51:134-141, 2019. PMID: 30964844