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Education:

     •     BA, University of Michigan (Ann Arbor, MI), 1981

     •     MD, University of Michigan (Ann Arbor, MI), 1983

     •     Postdoctoral Fellowship, University of Pittsburgh (Pittsburgh, PA), 1987-1989


Current Trainees:

     •     Postdoctoral Fellows: Heather Gunn, PhD; Jessica Levenson, PhD

     •     Medical Students: Gisela Delgado-Rosada (MS-2, San Juan Bautista School of Medicine, Caguas, PR)

     •     Undergraduate Students: Anthony Cugini, University of Pittsburgh Swanson School of Engineering

     •     Accepting Trainees: Yes


Research Interests:

Dr. Buysse has over 25 years of experience in sleep medicine research. His main areas of focus include sleep assessment and patient-reported outcomes; evaluation and treatment of insomnia; and sleep in aging. He has also investigated sleep in mood disorders, and the interaction between sleep and circadian physiology. This research uses a variety of techniques such as self-report, actigraphy, home and laboratory-based polysomnography, laboratory-based circadian assessments, and functional imaging studies. Dr. Buysse has also conducted clinical trials of behavioral treatment for insomnia.


Dr. Buysse has a long-standing record of teaching and mentoring. He has mentored (or is currently mentoring) 21 post-doctoral fellows, 11 of these as primary research mentor. He has also mentored 12 undergraduate or medical students on research electives. Nine of Dr. Buysse's previous post-docs have received K awards, eight have obtained NIH R-series funding, and four are still in training. Dr. Buysse is Program Director of an NHLBI-funded T32 program, “Translational Research Training in Sleep Medicine” (HL082610-08), and on the training faculty of two other T32 programs and the institutional KL2 program through the Clinical and Translational Science Institute. Of 8 alumni of the sleep medicine T32, 5 have received K awards. Dr. Buysse is the prior recipient of a K24 award.


Dr. Buysse has served in national and local leadership positions. He is Past President of the American Academy of Sleep Medicine, a former member of the Board of Directors of the Society of Behavioral Sleep Medicine, and Chair of the Sleep Research Network. He has served as Chair of the Biobehavioral Mechanisms of Stress and Health (MESH) study section at NIH, and has served on several NIH panels, including the Program Committee for the NIH State-of-the-Science Conference on the Manifestations and Management of Chronic Insomnia in Adults. Dr. Buysse is Deputy Editor of the journal SLEEP, and has served as Deputy Editor of Journal of Clinical Sleep Medicine, and Associate Editor of Behavioral Sleep Medicine. At the University of Pittsburgh, he served as Director of the Neuroscience Clinical and Translational Research Center, a component of our GCRC then CTSI, for nearly 20 years. He is Co-Chair of the Department of Psychiatry Research Review Committee, and Chair of the K Award Review Program.


Current Research Funding:

     •     1 R21 MH102412 (Role: PI): Dimensional Sleep Disturbance in Relation to Positive/Negative Affect Systems, 2014 - 2016.

        NIH RePORTER Link

     •     1 UH2 HL125103 (Role: PI):  Pragmatic Trial of Behavioral Interventions for Insomnia in Hypertensive Patients, 2014 -2019.     

        NIH RePORTER Link     

     •     5 P01 AG020677-09  5 P01 AG020677-09 (Role: PI): Aging Well, Sleeping Efficiently 2010 - 5/31/2015 NIH RePORTER Link

     •     T32 HL082610 (Role: Training Director): Translational Research Training in Sleep Medicine, 2007-2017 NIH RePORTER Link

     •     UL1 TR0000005 (Role: Core PI): University of Pittsburgh Clinical and Translational Science Institute, 2011 – 2016.

        NIH RePORTER Link

     •     7 R01 HL112646 (Role: Co-Investigator): Security and Vigilance in Military Couples: A Dynamic Model of Sleep, Interpersonal

        Relationships, and Health, 2012 – 2015. NIH RePORTER Link

     •     5 R01 DA033064 (Role: Co-Investigator): Behavioral and Neural Consequences of Sleep Loss on Adolescent Affective

        Function, 2011 – 2015. NIH RePORTER Link

     •     American Sleep Medicine Foundation Grant (Role: Co-Investigator): Quantifying the Diagnostic and Therapeutic Utility

        of Wrist Actigraphy in Insomnia, 2014-2015.

     •     R01 GM113243 (Role: Co-Investigator): Collaborative Research: A Statistical Framework for the Spectral Analysis of Nocturnal

       Electrophysiological Time Series, 2014-2017.  NIH RePORTER Link


Selected Publications:

Levenson JC, Kay DB, Buysse DJ. The pathophysiology of insomnia. Chest (in press). PMCID: In process

Kay DB, Buysse DJ, Germain A, Hall MH, Monk TH. Subjective-objective sleep discrepancy among older adults: Associations with insomnia diagnosis and insomnia treatment. Journal of Sleep Research (in press). PMCID: in process

Germain A, Richardson R, Stocker R, Mammen O, Hall MH, Bramoweth A, Begley A, Rode N, Frank E, Haas G, Buysse DJ. Treatment for insomnia in combat-exposed OEF/OIF/OND military veterans: Preliminary randomized controlled trial. Behaviour Research and Therapy, 61:78-88, 2014. PMCID: PMC4180045

Tyagi S, Resnick NM, Perera S, Monk TH, Hall M, Buysse DJ. Behavioral treatment of insomnia: Also effective for nocturia. Journal of the American Geriatrics Society, 62(1):54-60, 2014. PMCID: PMC4055528

Buysse DJ. Sleep health: Can we define it? Does it matter? Sleep, 37(1):9-17, 2014. PMCID: PMC3902880

Troxel W, Conrad T, Germain A, Buysse DJ. Predictors of treatment response to brief behavioral treatment of insomnia (BBTI) in older adults. Journal of Clinical Sleep Medicine, 9(12):1-9, 2013. PMCID: PMC3836339

Monk TH, Buysse DJ. Exposure to shift work as a risk factor for diabetes. Journal of Biological Rhythms,  28(5):356-359, 2013. PMCID: PMC4001827

Buysse DJ. Insomnia. JAMA-Journal of the American Medical Association, 309(7):706-716, 2013. PMCID: PMC3632369

Troxel W, Germain A, Buysse DJ. Clinical management of insomnia with Brief Behavioral Treatment (BBTI). Behavioral Sleep Medicine, 10(4): 266-279, 2012. PMCID: PMC3622949.

Yu L, Buysse DJ, Germain A, Moul DE, Stover A, Dodds NE, Johnston KL, Pilkonis PA. Development of short forms from PROMISTM Sleep Disturbance and Sleep-Related Impairment Item Banks. Behavioral Medicine, 10(1): 6-24, 2012. PMCID: PMC3261577

Buysse DJ, Germain A, Hall M, Monk TH, Nofzinger EA. A neurobiological model of insomnia. Drug Discovery Today: Disease Models, 8(4): 129-137, 2011. PMCID: PMC3212043.  

Buysse DJ, Germain A, Moul DE, Franzen PL, Brar LK, Fletcher ME, Begley A, Houck PR, Mazumdar S, Reynolds CF, Monk TH. Efficacy of brief behavioral treatment for chronic insomnia in older adults. Archives of Internal Medicine, 171(10):887-895, 2011.  PMCID: PMC3101289

Buysse DJ, Yu L, Moul DE, Germain A, Stover A, Dodds NE, Johnston KL, Shablesky-Cade MA, Pilkonis PA. Development and validation of patient-reported outcome measures for sleep disturbance and sleep-related impairments. Sleep, 33(6):781-92, 2010. PMCID: PMC2880437

Buysse DJ, Hall M, Strollo PJ, Kamarck TW, Owens J, Lee L, Reis SE, Matthews KA. Relationships between the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and clinical/ polysomnographic measures in a community sample. Journal of Clinical Sleep Medicine, 4(6)563-571, 2008. PMCID: PMC2603534

Buysse DJ, Angst J, Gamma A, Ajdacic V, Eich D, Rossler W. Prevalence, course and comorbidity of insomnia and depression in young adults. Sleep, 31(4):473-80, 2008. PMCID: PMC2279748

Nofzinger EA, Nissen C, Germain A, Moul D, Hall M, Price JC, Miewald JM, Buysse DJ. Regional cerebral metabolic correlates of WASO during sleep in insomnia. Journal of Clinical Sleep Medicine, 2(3):316-22, 2006.

Buysse DJ, Nofzinger EA, Germain A, Meltzer CC, Wood A, Ombao H, Kupfer DJ, Moore RY. Regional Brain Glucose Metabolism During Morning and Evening Wakefulness in Humans: Preliminary Findings.  Sleep, 27(7):1245-54, 2004.

Nofzinger EA, Buysse DJ, Germain A, Price JC, Miewald JM, Kupfer DJ. Functional neuroimaging evidence of hyperarousal in insomnia. American Journal of Psychiatry, 161(11):2126-31, 2004.

Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2):193-213, 1989.


Complete list of published work: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40800059/?sort=date&direction=ascending


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Daniel J. Buysse, M.D.

UPMC Professor of Sleep Medicine

Professor of Psychiatry and Clinical and Translational Science

University of Pittsburgh School of Medicine

3811 O'Hara St.

Pittsburgh, PA  15213


T: (412) 246-6413

F: (412) 246-5300

buyssedj@upmc.edu